SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2enp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2enp B/K PROTEIN
(Homo
sapiens) 		4 / 8 THR A  78
THR A  72
VAL A 105
VAL A  58
 None
 0.92A 1t86A-2enpA:
undetectable		 1t86A-2enpA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2enp B/K PROTEIN
(Homo
sapiens) 		4 / 5 TYR A  21
THR A  29
PHE A  89
LEU A 124
 None
 1.34A 3qelC-2enpA:
undetectable		 3qelC-2enpA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2enp B/K PROTEIN
(Homo
sapiens) 		4 / 5 PHE A 108
PRO A  56
VAL A  74
PHE A  83
 None
 1.22A 4z4cA-2enpA:
undetectable		 4z4cA-2enpA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2enp B/K PROTEIN
(Homo
sapiens) 		3 / 3 THR A  78
THR A  72
LEU A  15
 None
 0.59A 5m66D-2enpA:
undetectable		 5m66D-2enpA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2enp B/K PROTEIN
(Homo
sapiens) 		3 / 3 ARG A  98
PHE A  89
LEU A 129
 None
 0.85A 5veuA-2enpA:
undetectable		 5veuA-2enpA:
13.42