SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PO0_A_NPSA602_1 (SERUM ALBUMIN)	2eo0	HYPOTHETICAL PROTEIN ST1444 (Sulfurisphaera tokodaii)	4 / 8	LYS A 83 ALA A 82 GLY A 77 LEU A 56	None	0.68A	4po0A-2eo0A: undetectable	4po0A-2eo0A: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8V_B_MIYB1103_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	2eo0	HYPOTHETICAL PROTEIN ST1444 (Sulfurisphaera tokodaii)	5 / 12	ASP A 45 ILE A 46 ALA A 48 PHE A 27 VAL A 29	None	1.07A	4u8vB-2eo0A: undetectable	4u8vB-2eo0A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U8Y_B_MIYB1102_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	2eo0	HYPOTHETICAL PROTEIN ST1444 (Sulfurisphaera tokodaii)	5 / 12	ASP A 45 ILE A 46 ALA A 48 PHE A 27 VAL A 29	None	1.08A	4u8yB-2eo0A: undetectable	4u8yB-2eo0A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ5_B_ACTB404_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	2eo0	HYPOTHETICAL PROTEIN ST1444 (Sulfurisphaera tokodaii)	3 / 3	TYR A 134 ARG A 141 LYS A 138	None	1.36A	4wq5B-2eo0A: undetectable	4wq5B-2eo0A: 17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XV2_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2eo0	HYPOTHETICAL PROTEIN ST1444 (Sulfurisphaera tokodaii)	4 / 4	GLY A 26 VAL A 29 PHE A 90 ILE A 55	None	1.12A	4xv2B-2eo0A: undetectable	4xv2B-2eo0A: 19.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4PO0_A_NPSA602_1","SERUM ALBUMIN","2eo0","HYPOTHETICAL PROTEIN ST1444","Sulfurisphaera tokodaii",4,"LYS A  83;ALA A  82;GLY A  77;LEU A  56","None","0.68A","4po0A-2eo0A:undetectable","4po0A-2eo0A:15.21"],["4U8V_B_MIYB1103_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","2eo0","HYPOTHETICAL PROTEIN ST1444","Sulfurisphaera tokodaii",5,"ASP A  45;ILE A  46;ALA A  48;PHE A  27;VAL A  29","None","1.07A","4u8vB-2eo0A:undetectable","4u8vB-2eo0A:9.52"],["4U8Y_B_MIYB1102_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","2eo0","HYPOTHETICAL PROTEIN ST1444","Sulfurisphaera tokodaii",5,"ASP A  45;ILE A  46;ALA A  48;PHE A  27;VAL A  29","None","1.08A","4u8yB-2eo0A:undetectable","4u8yB-2eo0A:9.52"],["4WQ5_B_ACTB404_0","TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE","2eo0","HYPOTHETICAL PROTEIN ST1444","Sulfurisphaera tokodaii",3,"TYR A 134;ARG A 141;LYS A 138","None","1.36A","4wq5B-2eo0A:undetectable","4wq5B-2eo0A:17.91"],["4XV2_B_P06B801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2eo0","HYPOTHETICAL PROTEIN ST1444","Sulfurisphaera tokodaii",4,"GLY A  26;VAL A  29;PHE A  90;ILE A  55","None","1.12A","4xv2B-2eo0A:undetectable","4xv2B-2eo0A:19.29"]]