SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eo5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.17A 1ddsB-2eo5A:
undetectable		 1ddsB-2eo5A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 8 PHE A 265
GLY A 259
ARG A 260
LEU A 397
 None
 0.86A 1gsfC-2eo5A:
undetectable		 1gsfC-2eo5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A 168
LYS A 130
ALA A 214
VAL A 208
 None
 1.00A 1hk1A-2eo5A:
undetectable		 1hk1A-2eo5A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.20A 1jolA-2eo5A:
undetectable		 1jolA-2eo5A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.14A 1re7B-2eo5A:
undetectable		 1re7B-2eo5A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.17A 1tdrA-2eo5A:
2.1		 1tdrA-2eo5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PRO A  21
VAL A 414
SER A 376
ILE A 373
LEU A 411
 None
 1.42A 1z9hA-2eo5A:
undetectable		 1z9hA-2eo5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PRO A  21
VAL A 414
SER A 376
ILE A 373
LEU A 411
 None
 1.42A 1z9hB-2eo5A:
undetectable		 1z9hB-2eo5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PRO A  21
VAL A 414
SER A 376
ILE A 373
LEU A 411
 None
 1.42A 1z9hC-2eo5A:
undetectable		 1z9hC-2eo5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 8 VAL A 123
THR A 293
GLY A 113
THR A 114
 None
None
PLP  A1001 ( 3.4A)
PLP  A1001 ( 3.8A)
 0.86A 2a1hA-2eo5A:
undetectable
2a1hB-2eo5A:
undetectable		 2a1hA-2eo5A:
24.49
2a1hB-2eo5A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 356
GLY A 338
LEU A 397
GLY A 259
ALA A 358
 None
 0.91A 2fk8A-2eo5A:
undetectable		 2fk8A-2eo5A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 254
ASN A  81
SER A 110
ILE A 290
CYH A 317
 PLP  A1001 ( 4.3A)
None
None
None
None
 1.19A 2ft9A-2eo5A:
undetectable		 2ft9A-2eo5A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 10 PHE A 135
HIS A 140
ILE A 133
ALA A 151
VAL A 195
 None
 1.03A 2gl0A-2eo5A:
0.2
2gl0B-2eo5A:
0.0		 2gl0A-2eo5A:
20.48
2gl0B-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 PHE A 135
HIS A 140
ILE A 133
ALA A 151
VAL A 195
 None
 1.02A 2gl0B-2eo5A:
undetectable
2gl0C-2eo5A:
undetectable		 2gl0B-2eo5A:
20.48
2gl0C-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 PHE A 135
HIS A 140
THR A 150
ALA A 151
VAL A 195
 None
 1.26A 2gl0B-2eo5A:
undetectable
2gl0C-2eo5A:
undetectable		 2gl0B-2eo5A:
20.48
2gl0C-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 133
ALA A 151
VAL A 195
PHE A 135
HIS A 140
 None
 1.03A 2gl0A-2eo5A:
undetectable
2gl0C-2eo5A:
undetectable		 2gl0A-2eo5A:
20.48
2gl0C-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 THR A 150
ALA A 151
VAL A 195
PHE A 135
HIS A 140
 None
 1.28A 2gl0A-2eo5A:
undetectable
2gl0C-2eo5A:
undetectable		 2gl0A-2eo5A:
20.48
2gl0C-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A 135
HIS A 140
ILE A 133
ALA A 151
VAL A 195
 None
 1.06A 2gl0D-2eo5A:
undetectable
2gl0E-2eo5A:
undetectable		 2gl0D-2eo5A:
20.48
2gl0E-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A 135
HIS A 140
THR A 150
ALA A 151
VAL A 195
 None
 1.27A 2gl0D-2eo5A:
undetectable
2gl0E-2eo5A:
undetectable		 2gl0D-2eo5A:
20.48
2gl0E-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 PHE A 135
HIS A 140
ILE A 133
ALA A 151
VAL A 195
 None
 1.01A 2gl0E-2eo5A:
undetectable
2gl0F-2eo5A:
undetectable		 2gl0E-2eo5A:
20.48
2gl0F-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 PHE A 135
HIS A 140
THR A 150
ALA A 151
VAL A 195
 None
 1.28A 2gl0E-2eo5A:
undetectable
2gl0F-2eo5A:
undetectable		 2gl0E-2eo5A:
20.48
2gl0F-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A 133
ALA A 151
VAL A 195
PHE A 135
HIS A 140
 None
 1.04A 2gl0D-2eo5A:
undetectable
2gl0F-2eo5A:
undetectable		 2gl0D-2eo5A:
20.48
2gl0F-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 THR A 150
ALA A 151
VAL A 195
PHE A 135
HIS A 140
 None
 1.26A 2gl0D-2eo5A:
undetectable
2gl0F-2eo5A:
undetectable		 2gl0D-2eo5A:
20.48
2gl0F-2eo5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 THR A 143
SER A 146
ALA A 116
GLY A 113
SER A 112
 None
None
None
PLP  A1001 ( 3.4A)
PLP  A1001 ( 3.8A)
 1.18A 2xf3A-2eo5A:
0.0		 2xf3A-2eo5A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 THR A 143
SER A 146
ALA A 116
GLY A 113
SER A 112
 None
None
None
PLP  A1001 ( 3.4A)
PLP  A1001 ( 3.8A)
 1.18A 2xf3B-2eo5A:
0.0		 2xf3B-2eo5A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ALA A 282
VAL A 327
ILE A 324
GLY A 320
ILE A 319
 None
 1.14A 3el4B-2eo5A:
undetectable		 3el4B-2eo5A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 221
ILE A 355
LYS A 339
GLY A 338
LEU A 397
 None
 0.82A 3em0B-2eo5A:
undetectable		 3em0B-2eo5A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 ILE A 216
TYR A 245
ILE A 203
HIS A 169
 None
 1.10A 3eteB-2eo5A:
undetectable
3eteC-2eo5A:
undetectable		 3eteB-2eo5A:
23.13
3eteC-2eo5A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 112
GLY A 113
THR A 114
 PLP  A1001 ( 3.8A)
PLP  A1001 ( 3.4A)
PLP  A1001 ( 3.8A)
 0.21A 3k9wA-2eo5A:
undetectable		 3k9wA-2eo5A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 8 GLY A  57
SER A  60
GLY A 285
ILE A 326
VAL A  64
 None
 1.24A 3v1nA-2eo5A:
undetectable		 3v1nA-2eo5A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ARG A 260
GLY A 259
LEU A  56
LEU A 258
ILE A 326
 None
 1.26A 3wdmA-2eo5A:
3.2		 3wdmA-2eo5A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 9 ALA A 280
GLY A 284
LEU A  95
LEU A 258
ILE A 324
 PLP  A1001 ( 4.5A)
None
None
None
None
 1.17A 3wdmC-2eo5A:
3.2		 3wdmC-2eo5A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A 296
GLY A 215
ILE A 132
VAL A 124
ILE A 121
 None
 1.11A 4aztA-2eo5A:
undetectable		 4aztA-2eo5A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A 224
GLY A 223
SER A 152
 None
 0.69A 4b53B-2eo5A:
undetectable		 4b53B-2eo5A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 TYR A 227
THR A  48
PRO A 396
ASN A  55
VAL A 334
 None
 1.41A 4eb6B-2eo5A:
undetectable
4eb6C-2eo5A:
2.7		 4eb6B-2eo5A:
22.25
4eb6C-2eo5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  95
VAL A 327
LEU A 264
ALA A 282
LEU A 283
 None
 1.45A 4m11A-2eo5A:
undetectable		 4m11A-2eo5A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.21A 4qi9C-2eo5A:
undetectable		 4qi9C-2eo5A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 GLU A 219
ARG A 353
GLY A 226
GLY A 223
 PLP  A1001 ( 4.0A)
None
None
None
 0.86A 4rdxA-2eo5A:
undetectable		 4rdxA-2eo5A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A 284
GLY A 286
GLY A  57
LEU A  56
ALA A 316
LEU A 283
 None
 1.40A 5c0oG-2eo5A:
2.9		 5c0oG-2eo5A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  51
ASP A  46
ILE A 373
LEU A  23
TYR A 227
 None
 1.17A 5hi6B-2eo5A:
undetectable		 5hi6B-2eo5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A  51
GLY A  50
LEU A 264
PHE A 265
 None
 0.68A 5hieB-2eo5A:
undetectable		 5hieB-2eo5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A 139
GLY A 223
GLY A 257
LEU A 258
GLY A 141
 PLP  A1001 ( 4.9A)
None
None
None
PLP  A1001 ( 4.2A)
 1.30A 5i71A-2eo5A:
undetectable		 5i71A-2eo5A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 124
VAL A 250
GLY A 141
THR A 143
PHE A 144
 None
None
PLP  A1001 ( 4.2A)
None
None
 1.21A 5igiA-2eo5A:
undetectable		 5igiA-2eo5A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 138
GLY A  52
ILE A  51
GLY A 226
GLY A 225
 None
 0.85A 5koxA-2eo5A:
undetectable		 5koxA-2eo5A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 10 ALA A 342
LEU A 345
ILE A 340
ALA A 404
ILE A 399
 None
 0.97A 5mvmD-2eo5A:
undetectable
5mvmE-2eo5A:
undetectable		 5mvmD-2eo5A:
11.57
5mvmE-2eo5A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A 294
VAL A 273
ILE A 267
LEU A 279
LEU A 264
 None
 0.86A 5tiwA-2eo5A:
undetectable		 5tiwA-2eo5A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLN A 239
ALA A 236
LEU A 249
ILE A 216
ASP A 252
 None
None
None
None
PLP  A1001 ( 3.0A)
 1.12A 5vlmG-2eo5A:
0.0		 5vlmG-2eo5A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2eo5 419AA LONG
HYPOTHETICAL
AMINOTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  57
LEU A  56
GLY A 286
TRP A  35
VAL A  53
 None
 0.98A 6mhtA-2eo5A:
undetectable		 6mhtA-2eo5A:
23.83