SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eoq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2eoq	ZINC FINGER PROTEIN 224 (Homo sapiens)	4 / 5	HIS A 31 CYH A 15 ILE A 17 HIS A 35	ZN A 201 ( 3.2A) ZN A 201 ( 2.3A) ZN A 201 ( 4.2A) ZN A 201 ( 3.1A)	1.43A	3qpkA-2eoqA: undetectable	3qpkA-2eoqA: 7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_B_CUB601_0 (LACCASE-1)	2eoq	ZINC FINGER PROTEIN 224 (Homo sapiens)	4 / 4	HIS A 31 CYH A 15 ILE A 17 HIS A 35	ZN A 201 ( 3.2A) ZN A 201 ( 2.3A) ZN A 201 ( 4.2A) ZN A 201 ( 3.1A)	1.41A	3qpkB-2eoqA: undetectable	3qpkB-2eoqA: 7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKD_A_CYZA266_2 (GLUTAMATE RECEPTOR 2)	2eoq	ZINC FINGER PROTEIN 224 (Homo sapiens)	4 / 5	ILE A 17 SER A 21 LYS A 20 GLY A 19	ZN A 201 ( 4.2A) None None None	1.15A	3tkdB-2eoqA: undetectable	3tkdB-2eoqA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKD_B_CYZB267_1 (GLUTAMATE RECEPTOR 2)	2eoq	ZINC FINGER PROTEIN 224 (Homo sapiens)	4 / 5	ILE A 17 SER A 21 LYS A 20 GLY A 19	ZN A 201 ( 4.2A) None None None	1.15A	3tkdA-2eoqA: undetectable	3tkdA-2eoqA: 12.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3QPK_A_CUA601_0","LACCASE-1","2eoq","ZINC FINGER PROTEIN 224","Homo sapiens",4,"HIS A  31;CYH A  15;ILE A  17;HIS A  35"," ZN A 201 ( 3.2A); ZN A 201 ( 2.3A); ZN A 201 ( 4.2A); ZN A 201 ( 3.1A)","1.43A","3qpkA-2eoqA:undetectable","3qpkA-2eoqA:7.02"],["3QPK_B_CUB601_0","LACCASE-1","2eoq","ZINC FINGER PROTEIN 224","Homo sapiens",4,"HIS A  31;CYH A  15;ILE A  17;HIS A  35"," ZN A 201 ( 3.2A); ZN A 201 ( 2.3A); ZN A 201 ( 4.2A); ZN A 201 ( 3.1A)","1.41A","3qpkB-2eoqA:undetectable","3qpkB-2eoqA:7.02"],["3TKD_A_CYZA266_2","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","2eoq","ZINC FINGER PROTEIN 224","Homo sapiens",4,"ILE A  17;SER A  21;LYS A  20;GLY A  19"," ZN A 201 ( 4.2A);None;None;None","1.15A","3tkdB-2eoqA:undetectable","3tkdB-2eoqA:12.99"],["3TKD_B_CYZB267_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","2eoq","ZINC FINGER PROTEIN 224","Homo sapiens",4,"ILE A  17;SER A  21;LYS A  20;GLY A  19"," ZN A 201 ( 4.2A);None;None;None","1.15A","3tkdA-2eoqA:undetectable","3tkdA-2eoqA:12.99"]]