SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 5 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.33A 3qpkA-2eosA:
undetectable		 3qpkA-2eosA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.29A 3qpkB-2eosA:
undetectable		 3qpkB-2eosA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.40A 5mejA-2eosA:
undetectable		 5mejA-2eosA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.40A 5mewA-2eosA:
undetectable		 5mewA-2eosA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mhuA-2eosA:
undetectable		 5mhuA-2eosA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mhvA-2eosA:
undetectable		 5mhvA-2eosA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mhwA-2eosA:
undetectable		 5mhwA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.40A 5mhxA-2eosA:
undetectable		 5mhxA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.40A 5mhyA-2eosA:
undetectable		 5mhyA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mhzA-2eosA:
undetectable		 5mhzA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mi1A-2eosA:
undetectable		 5mi1A-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mi2A-2eosA:
undetectable		 5mi2A-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5miaA-2eosA:
undetectable		 5miaA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mibA-2eosA:
undetectable		 5mibA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5micA-2eosA:
undetectable		 5micA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5midA-2eosA:
undetectable		 5midA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5mieA-2eosA:
undetectable		 5mieA-2eosA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 2eos B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 4 HIS A  30
CYH A  14
ILE A  16
HIS A  34
 ZN  A 201 ( 3.2A)
ZN  A 201 ( 2.3A)
ZN  A 201 ( 4.1A)
ZN  A 201 ( 3.1A)
 1.39A 5migA-2eosA:
undetectable		 5migA-2eosA:
8.28