SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ep6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 2ep6 MCTP2 PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 120
LEU A 175
GLY A 176
LEU A 109
 None
 0.88A 1ya4B-2ep6A:
undetectable		 1ya4B-2ep6A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2ep6 MCTP2 PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 154
LEU A 126
GLY A 127
 None
 0.51A 4xmfA-2ep6A:
undetectable		 4xmfA-2ep6A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2ep6 MCTP2 PROTEIN
(Homo
sapiens) 		4 / 7 ASN A 139
LYS A 138
LEU A 110
PHE A 204
 None
 1.23A 4yv5A-2ep6A:
undetectable		 4yv5A-2ep6A:
23.24