SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ep8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2ep8 PESCADILLO HOMOLOG 1
(Homo
sapiens) 		4 / 8 HIS A 375
VAL A 410
ARG A 390
GLY A 389
 None
 0.84A 2xfsA-2ep8A:
undetectable		 2xfsA-2ep8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2ep8 PESCADILLO HOMOLOG 1
(Homo
sapiens) 		4 / 8 HIS A 375
VAL A 410
ARG A 390
GLY A 389
 None
 0.85A 2xh9A-2ep8A:
undetectable		 2xh9A-2ep8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 2ep8 PESCADILLO HOMOLOG 1
(Homo
sapiens) 		4 / 8 ARG A 390
VAL A 378
VAL A 338
GLN A 384
 None
 1.12A 3uy4A-2ep8A:
undetectable		 3uy4A-2ep8A:
15.03