SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2epr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2epr	POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	HIS A 373 CYH A 357 ILE A 359 HIS A 377	ZN A 201 ( 3.2A) ZN A 201 (-2.3A) ZN A 201 (-4.3A) ZN A 201 ( 3.1A)	1.44A	3qpkA-2eprA: undetectable	3qpkA-2eprA: 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_B_CUB601_0 (LACCASE-1)	2epr	POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 4	HIS A 373 CYH A 357 ILE A 359 HIS A 377	ZN A 201 ( 3.2A) ZN A 201 (-2.3A) ZN A 201 (-4.3A) ZN A 201 ( 3.1A)	1.43A	3qpkB-2eprA: undetectable	3qpkB-2eprA: 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OS7_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	2epr	POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 (Homo sapiens)	3 / 3	HIS A 377 SER A 378 LYS A 381	ZN A 201 ( 3.1A) None None	1.24A	5os7A-2eprA: undetectable	5os7A-2eprA: 12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GMD_B_ACTB402_0 (CASEIN KINASE II SUBUNIT ALPHA)	2epr	POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1 (Homo sapiens)	3 / 3	HIS A 377 SER A 378 LYS A 381	ZN A 201 ( 3.1A) None None	1.24A	6gmdB-2eprA: undetectable	6gmdB-2eprA: 12.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3QPK_A_CUA601_0","LACCASE-1","2epr","POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1","Homo sapiens",4,"HIS A 373;CYH A 357;ILE A 359;HIS A 377"," ZN A 201 ( 3.2A); ZN A 201 (-2.3A); ZN A 201 (-4.3A); ZN A 201 ( 3.1A)","1.44A","3qpkA-2eprA:undetectable","3qpkA-2eprA:5.56"],["3QPK_B_CUB601_0","LACCASE-1","2epr","POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1","Homo sapiens",4,"HIS A 373;CYH A 357;ILE A 359;HIS A 377"," ZN A 201 ( 3.2A); ZN A 201 (-2.3A); ZN A 201 (-4.3A); ZN A 201 ( 3.1A)","1.43A","3qpkB-2eprA:undetectable","3qpkB-2eprA:5.56"],["5OS7_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","2epr","POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1","Homo sapiens",3,"HIS A 377;SER A 378;LYS A 381"," ZN A 201 ( 3.1A);None;None","1.24A","5os7A-2eprA:undetectable","5os7A-2eprA:12.81"],["6GMD_B_ACTB402_0","CASEIN KINASE II SUBUNIT ALPHA","2epr","POZ-, AT HOOK-, AND ZINC FINGER-CONTAINING PROTEIN 1","Homo sapiens",3,"HIS A 377;SER A 378;LYS A 381"," ZN A 201 ( 3.1A);None;None","1.24A","6gmdB-2eprA:undetectable","6gmdB-2eprA:12.81"]]