SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AGM_A_ACRA495_1 (GLUCOAMYLASE-471)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	ALA A 200 TYR A 195 GLU A 174 ARG A 168 TRP A 164	None	1.39A	1agmA-2eq9A: undetectable	1agmA-2eq9A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AGM_A_ACRA496_1 (GLUCOAMYLASE-471)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	ALA A 200 TYR A 195 GLU A 174 ARG A 168 TRP A 164	None	1.39A	1agmA-2eq9A: undetectable	1agmA-2eq9A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_A_PFLA4002_1 (SERUM ALBUMIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	PHE A 413 LEU A 212 SER A 350	None	0.95A	1e7aA-2eq9A: 2.9	1e7aA-2eq9A: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_D_DVAD6_0 (GRAMICIDIN A)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 4	VAL A 398 TRP A 358 ALA A 359 VAL A 415	None	1.41A	1gmkC-2eq9A: undetectable 1gmkD-2eq9A: undetectable	1gmkC-2eq9A: 3.06 1gmkD-2eq9A: 3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K6C_B_MK1B902_1 (POL POLYPROTEIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 10	ALA A 322 GLY A 44 GLY A 45 PRO A 54 THR A 55	FAD A8482 (-3.4A) None FAD A8482 (-3.0A) None FAD A8482 (-4.3A)	1.10A	1k6cA-2eq9A: undetectable	1k6cA-2eq9A: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_C_ADNC2502_2 (ADENOSYLHOMOCYSTEINA SE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	GLU A 357 THR A 354 LEU A 212	None	0.57A	1v8bC-2eq9A: 4.2	1v8bC-2eq9A: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	ARG A 235 VAL A 268 GLY A 156	None	0.43A	2avvE-2eq9A: undetectable	2avvE-2eq9A: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JFA_A_RALA600_2 (ESTROGEN RECEPTOR)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 439 ASP A 407 MET A 432 LEU A 428	None	1.26A	2jfaA-2eq9A: undetectable	2jfaA-2eq9A: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 8	LEU A 107 LEU A 12 GLY A 329 MET A 326	None	0.95A	2po5B-2eq9A: undetectable	2po5B-2eq9A: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_A_RALA600_2 (ESTROGEN RECEPTOR)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 439 ASP A 407 MET A 432 LEU A 428	None	1.24A	2qxsA-2eq9A: undetectable	2qxsA-2eq9A: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_B_RALB600_2 (ESTROGEN RECEPTOR)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 439 ASP A 407 MET A 432 LEU A 428	None	1.26A	2qxsB-2eq9A: undetectable	2qxsB-2eq9A: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3K_A_SAMA1254_0 (ESSENTIAL FOR MITOTIC GROWTH 1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 10	LEU A 283 VAL A 288 GLY A 287 GLY A 280 LEU A 281	None None None None FAD A8482 (-4.7A)	0.94A	2v3kA-2eq9A: 2.2	2v3kA-2eq9A: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1161_1 (ALLERGEN ARG R 1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	VAL A 252 TYR A 243 VAL A 163 ASP A 162	None	1.05A	2x45A-2eq9A: undetectable	2x45A-2eq9A: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_B_HSMB1162_1 (ALLERGEN ARG R 1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	GLU A 455 HIS A 446 GLU A 451	None	0.85A	2x45B-2eq9A: undetectable	2x45B-2eq9A: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1161_1 (ALLERGEN ARG R 1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	VAL A 252 TYR A 243 VAL A 163 ASP A 162	None	1.16A	2x45C-2eq9A: undetectable	2x45C-2eq9A: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN7_A_T44A1355_1 (THYROXINE-BINDING GLOBULIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 10	LEU A 83 LEU A 88 LEU A 58 LEU A 198 ARG A 197	None	1.02A	2xn7A-2eq9A: undetectable 2xn7B-2eq9A: undetectable	2xn7A-2eq9A: 22.57 2xn7B-2eq9A: 5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBZ_A_VDXA501_1 (CYTOCHROME P450-SU1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	6 / 11	VAL A 194 VAL A 202 ARG A 197 SER A 355 ILE A 232 ALA A 271	None	1.42A	2zbzA-2eq9A: undetectable	2zbzA-2eq9A: 24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AVP_A_MV2A313_1 (PANTOTHENATE KINASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 7	VAL A 400 ASP A 407 HIS A 461 LEU A 409	None	0.98A	3avpA-2eq9A: undetectable	3avpA-2eq9A: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B0W_B_DGXB1_1 (NUCLEAR RECEPTOR ROR-GAMMA)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	LEU A 175 ALA A 62 ALA A 200 VAL A 202 LEU A 223	None	1.35A	3b0wB-2eq9A: undetectable	3b0wB-2eq9A: 20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F33_A_PFLA2001_1 (FERRITIN LIGHT CHAIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 6	LEU A 115 LEU A 107 ARG A 116 LEU A 36	None	0.97A	3f33A-2eq9A: undetectable	3f33A-2eq9A: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FAL_A_REAA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 10	ALA A 457 ALA A 456 ALA A 440 VAL A 361 ILE A 423	None	1.11A	3falA-2eq9A: undetectable	3falA-2eq9A: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	ALA A 426 LEU A 436 LEU A 439 SER A 450 GLY A 402	None	1.36A	3lbdA-2eq9A: undetectable	3lbdA-2eq9A: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O14_A_NIOA300_1 (ANTI-ECFSIGMA FACTOR, CHRR)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 7	ALA A 311 VAL A 306 VAL A 309 LEU A 145	None	0.76A	3o14A-2eq9A: undetectable	3o14A-2eq9A: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_0 (YAEB-LIKE PROTEIN RPA0152)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	LYS A 86 ARG A 92 LYS A 267	None	0.99A	3okxA-2eq9A: undetectable	3okxA-2eq9A: 16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	VAL A 187 SER A 166 GLY A 273 ARG A 274	FAD A8482 ( 4.5A) FAD A8482 (-3.6A) None FAD A8482 (-3.6A)	1.30A	3v4tA-2eq9A: undetectable 3v4tD-2eq9A: 1.5	3v4tA-2eq9A: 23.78 3v4tD-2eq9A: 23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	VAL A 272 VAL A 265 PHE A 157 LEU A 254 VAL A 263	None	1.16A	3w68C-2eq9A: undetectable	3w68C-2eq9A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 175 TYR A 195 LEU A 58 ARG A 92	None	1.44A	4em2A-2eq9A: undetectable	4em2A-2eq9A: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1Z_A_MXMA807_1 (PROSTAGLANDIN G/H SYNTHASE 1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	ILE A 15 VAL A 38 LEU A 115 GLY A 134 LEU A 281	FAD A8482 (-4.5A) FAD A8482 ( 4.8A) None None FAD A8482 (-4.7A)	0.90A	4o1zA-2eq9A: undetectable	4o1zA-2eq9A: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4S0V_A_SUVA2001_1 (HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	THR A 304 VAL A 306 THR A 278 GLU A 284 ILE A 15	None None None None FAD A8482 (-4.5A)	1.49A	4s0vA-2eq9A: 3.0	4s0vA-2eq9A: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_2 (ESTROGEN RECEPTOR)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 48 GLU A 42 LEU A 107 HIS A 23	None	1.13A	4xi3B-2eq9A: undetectable	4xi3B-2eq9A: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJZ_B_BEZB601_0 (BENZOATE-COENZYME A LIGASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 8	ALA A 146 VAL A 14 GLY A 20 ALA A 325 GLY A 329	FAD A8482 (-4.7A) None FAD A8482 (-3.5A) FAD A8482 (-3.6A) None	1.24A	4zjzB-2eq9A: undetectable	4zjzB-2eq9A: 23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J7W_C_MTXC402_1 (THYMIDYLATE SYNTHASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	GLU A 334 ILE A 331 LEU A 12 ILE A 312 ALA A 146	None None None None FAD A8482 (-4.7A)	1.09A	5j7wC-2eq9A: undetectable	5j7wC-2eq9A: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J7W_D_MTXD402_1 (THYMIDYLATE SYNTHASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	GLU A 334 ILE A 331 LEU A 12 ILE A 312 ALA A 146	None None None None FAD A8482 (-4.7A)	1.08A	5j7wD-2eq9A: undetectable	5j7wD-2eq9A: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	GLY A 18 GLY A 20 VAL A 103 VAL A 46 LEU A 48	FAD A8482 (-3.6A) FAD A8482 (-3.5A) None FAD A8482 ( 3.9A) None	1.18A	5kocB-2eq9A: undetectable	5kocB-2eq9A: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L6E_B_ACTB401_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT N6-ADENOSINE-METHYLT RANSFERASE SUBUNIT METTL14)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 6	GLU A 228 LEU A 204 ARG A 235 ARG A 224	None	1.04A	5l6eA-2eq9A: undetectable 5l6eB-2eq9A: undetectable	5l6eA-2eq9A: 18.24 5l6eB-2eq9A: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L94_A_TESA502_1 (CYTOCHROME P450)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 8	VAL A 268 ILE A 182 THR A 203 VAL A 263 VAL A 265	None	1.47A	5l94A-2eq9A: undetectable	5l94A-2eq9A: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_1 (SCRFP-TAG,GP41)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	GLY A 139 LYS A 125 LEU A 114 GLU A 113 LEU A 115	None	1.14A	5nwwA-2eq9A: undetectable	5nwwA-2eq9A: 5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U63_A_ACTA405_0 (THIOREDOXIN REDUCTASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	GLY A 329 LEU A 330 HIS A 23	None	0.71A	5u63A-2eq9A: 27.0	5u63A-2eq9A: 24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U63_B_ACTB405_0 (THIOREDOXIN REDUCTASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	GLY A 329 LEU A 330 HIS A 23	None	0.69A	5u63B-2eq9A: 26.9	5u63B-2eq9A: 24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VW5_A_NCAA403_0 (FERREDOXIN--NADP REDUCTASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 8	GLY A 20 GLY A 329 LEU A 330 ALA A 333	FAD A8482 (-3.5A) None None None	0.75A	5vw5A-2eq9A: 2.2	5vw5A-2eq9A: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_B_ADNB503_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	4 / 5	LEU A 180 VAL A 263 GLU A 261 LEU A 254	None	1.03A	5xooB-2eq9A: undetectable	5xooB-2eq9A: 10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZHM_B_SAMB301_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	6 / 12	LEU A 106 GLY A 104 GLU A 39 LEU A 99 GLY A 101 GLY A 102	None None FAD A8482 (-2.7A) None None None	1.21A	5zhmB-2eq9A: undetectable	5zhmB-2eq9A: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZHM_B_SAMB301_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	6 / 12	LEU A 106 GLY A 104 GLU A 42 LEU A 99 GLY A 101 GLY A 102	None	1.50A	5zhmB-2eq9A: undetectable	5zhmB-2eq9A: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_D_GLYD713_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	3 / 3	ARG A 327 HIS A 23 ARG A 27	None	0.87A	6dwdD-2eq9A: undetectable	6dwdD-2eq9A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_2 (-)	2eq9	PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT (Thermus thermophilus)	5 / 12	VAL A 298 ASP A 291 GLU A 150 PRO A 318 GLY A 313	None None None None FAD A8482 (-3.4A)	1.34A	6gnfC-2eq9A: undetectable	6gnfC-2eq9A: 23.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AGM_A_ACRA495_1","GLUCOAMYLASE-471","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 200;TYR A 195;GLU A 174;ARG A 168;TRP A 164","None","1.39A","1agmA-2eq9A:undetectable","1agmA-2eq9A:21.52"],["1AGM_A_ACRA496_1","GLUCOAMYLASE-471","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 200;TYR A 195;GLU A 174;ARG A 168;TRP A 164","None","1.39A","1agmA-2eq9A:undetectable","1agmA-2eq9A:21.52"],["1E7A_A_PFLA4002_1","SERUM ALBUMIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"PHE A 413;LEU A 212;SER A 350","None","0.95A","1e7aA-2eq9A:2.9","1e7aA-2eq9A:22.26"],["1GMK_D_DVAD6_0","GRAMICIDIN A","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"VAL A 398;TRP A 358;ALA A 359;VAL A 415","None","1.41A","1gmkC-2eq9A:undetectable;1gmkD-2eq9A:undetectable","1gmkC-2eq9A:3.06;1gmkD-2eq9A:3.06"],["1K6C_B_MK1B902_1","POL POLYPROTEIN;POL POLYPROTEIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 322;GLY A  44;GLY A  45;PRO A  54;THR A  55","FAD A8482 (-3.4A);None;FAD A8482 (-3.0A);None;FAD A8482 (-4.3A)","1.10A","1k6cA-2eq9A:undetectable","1k6cA-2eq9A:10.94"],["1V8B_C_ADNC2502_2","ADENOSYLHOMOCYSTEINASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"GLU A 357;THR A 354;LEU A 212","None","0.57A","1v8bC-2eq9A:4.2","1v8bC-2eq9A:22.62"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"ARG A 235;VAL A 268;GLY A 156","None","0.43A","2avvE-2eq9A:undetectable","2avvE-2eq9A:12.99"],["2JFA_A_RALA600_2","ESTROGEN RECEPTOR","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 439;ASP A 407;MET A 432;LEU A 428","None","1.26A","2jfaA-2eq9A:undetectable","2jfaA-2eq9A:19.28"],["2PO5_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 107;LEU A  12;GLY A 329;MET A 326","None","0.95A","2po5B-2eq9A:undetectable","2po5B-2eq9A:22.18"],["2QXS_A_RALA600_2","ESTROGEN RECEPTOR","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 439;ASP A 407;MET A 432;LEU A 428","None","1.24A","2qxsA-2eq9A:undetectable","2qxsA-2eq9A:21.70"],["2QXS_B_RALB600_2","ESTROGEN RECEPTOR","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 439;ASP A 407;MET A 432;LEU A 428","None","1.26A","2qxsB-2eq9A:undetectable","2qxsB-2eq9A:21.70"],["2V3K_A_SAMA1254_0","ESSENTIAL FOR MITOTIC GROWTH 1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"LEU A 283;VAL A 288;GLY A 287;GLY A 280;LEU A 281","None;None;None;None;FAD A8482 (-4.7A)","0.94A","2v3kA-2eq9A:2.2","2v3kA-2eq9A:22.27"],["2X45_A_HSMA1161_1","ALLERGEN ARG R 1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"VAL A 252;TYR A 243;VAL A 163;ASP A 162","None","1.05A","2x45A-2eq9A:undetectable","2x45A-2eq9A:15.90"],["2X45_B_HSMB1162_1","ALLERGEN ARG R 1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"GLU A 455;HIS A 446;GLU A 451","None","0.85A","2x45B-2eq9A:undetectable","2x45B-2eq9A:15.90"],["2X45_C_HSMC1161_1","ALLERGEN ARG R 1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"VAL A 252;TYR A 243;VAL A 163;ASP A 162","None","1.16A","2x45C-2eq9A:undetectable","2x45C-2eq9A:15.90"],["2XN7_A_T44A1355_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"LEU A  83;LEU A  88;LEU A  58;LEU A 198;ARG A 197","None","1.02A","2xn7A-2eq9A:undetectable;2xn7B-2eq9A:undetectable","2xn7A-2eq9A:22.57;2xn7B-2eq9A:5.78"],["2ZBZ_A_VDXA501_1","CYTOCHROME P450-SU1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",6,"VAL A 194;VAL A 202;ARG A 197;SER A 355;ILE A 232;ALA A 271","None","1.42A","2zbzA-2eq9A:undetectable","2zbzA-2eq9A:24.04"],["3AVP_A_MV2A313_1","PANTOTHENATE KINASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"VAL A 400;ASP A 407;HIS A 461;LEU A 409","None","0.98A","3avpA-2eq9A:undetectable","3avpA-2eq9A:21.67"],["3B0W_B_DGXB1_1","NUCLEAR RECEPTOR ROR-GAMMA","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"LEU A 175;ALA A  62;ALA A 200;VAL A 202;LEU A 223","None","1.35A","3b0wB-2eq9A:undetectable","3b0wB-2eq9A:20.05"],["3F33_A_PFLA2001_1","FERRITIN LIGHT CHAIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 115;LEU A 107;ARG A 116;LEU A  36","None","0.97A","3f33A-2eq9A:undetectable","3f33A-2eq9A:16.89"],["3FAL_A_REAA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 457;ALA A 456;ALA A 440;VAL A 361;ILE A 423","None","1.11A","3falA-2eq9A:undetectable","3falA-2eq9A:20.09"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 426;LEU A 436;LEU A 439;SER A 450;GLY A 402","None","1.36A","3lbdA-2eq9A:undetectable","3lbdA-2eq9A:21.32"],["3O14_A_NIOA300_1","ANTI-ECFSIGMA FACTOR, CHRR","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"ALA A 311;VAL A 306;VAL A 309;LEU A 145","None","0.76A","3o14A-2eq9A:undetectable","3o14A-2eq9A:18.80"],["3OKX_B_SAMB201_0","YAEB-LIKE PROTEIN RPA0152","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"LYS A  86;ARG A  92;LYS A 267","None","0.99A","3okxA-2eq9A:undetectable","3okxA-2eq9A:16.59"],["3V4T_A_ACTA502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"VAL A 187;SER A 166;GLY A 273;ARG A 274","FAD A8482 ( 4.5A);FAD A8482 (-3.6A);None;FAD A8482 (-3.6A)","1.30A","3v4tA-2eq9A:undetectable;3v4tD-2eq9A:1.5","3v4tA-2eq9A:23.78;3v4tD-2eq9A:23.78"],["3W68_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"VAL A 272;VAL A 265;PHE A 157;LEU A 254;VAL A 263","None","1.16A","3w68C-2eq9A:undetectable","3w68C-2eq9A:22.22"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 175;TYR A 195;LEU A  58;ARG A  92","None","1.44A","4em2A-2eq9A:undetectable","4em2A-2eq9A:16.53"],["4O1Z_A_MXMA807_1","PROSTAGLANDIN G\/H SYNTHASE 1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ILE A  15;VAL A  38;LEU A 115;GLY A 134;LEU A 281","FAD A8482 (-4.5A);FAD A8482 ( 4.8A);None;None;FAD A8482 (-4.7A)","0.90A","4o1zA-2eq9A:undetectable","4o1zA-2eq9A:20.10"],["4S0V_A_SUVA2001_1","HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"THR A 304;VAL A 306;THR A 278;GLU A 284;ILE A  15","None;None;None;None;FAD A8482 (-4.5A)","1.49A","4s0vA-2eq9A:3.0","4s0vA-2eq9A:21.48"],["4XI3_B_29SB601_2","ESTROGEN RECEPTOR","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A  48;GLU A  42;LEU A 107;HIS A  23","None","1.13A","4xi3B-2eq9A:undetectable","4xi3B-2eq9A:19.74"],["4ZJZ_B_BEZB601_0","BENZOATE-COENZYME A LIGASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"ALA A 146;VAL A  14;GLY A  20;ALA A 325;GLY A 329","FAD A8482 (-4.7A);None;FAD A8482 (-3.5A);FAD A8482 (-3.6A);None","1.24A","4zjzB-2eq9A:undetectable","4zjzB-2eq9A:23.99"],["5J7W_C_MTXC402_1","THYMIDYLATE SYNTHASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"GLU A 334;ILE A 331;LEU A  12;ILE A 312;ALA A 146","None;None;None;None;FAD A8482 (-4.7A)","1.09A","5j7wC-2eq9A:undetectable","5j7wC-2eq9A:21.68"],["5J7W_D_MTXD402_1","THYMIDYLATE SYNTHASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"GLU A 334;ILE A 331;LEU A  12;ILE A 312;ALA A 146","None;None;None;None;FAD A8482 (-4.7A)","1.08A","5j7wD-2eq9A:undetectable","5j7wD-2eq9A:21.68"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"GLY A  18;GLY A  20;VAL A 103;VAL A  46;LEU A  48","FAD A8482 (-3.6A);FAD A8482 (-3.5A);None;FAD A8482 ( 3.9A);None","1.18A","5kocB-2eq9A:undetectable","5kocB-2eq9A:21.92"],["5L6E_B_ACTB401_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT;N6-ADENOSINE-METHYLTRANSFERASE SUBUNIT METTL14","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"GLU A 228;LEU A 204;ARG A 235;ARG A 224","None","1.04A","5l6eA-2eq9A:undetectable;5l6eB-2eq9A:undetectable","5l6eA-2eq9A:18.24;5l6eB-2eq9A:19.70"],["5L94_A_TESA502_1","CYTOCHROME P450","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"VAL A 268;ILE A 182;THR A 203;VAL A 263;VAL A 265","None","1.47A","5l94A-2eq9A:undetectable","5l94A-2eq9A:22.75"],["5NWW_A_ACAA18_1","SCRFP-TAG,GP41","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"GLY A 139;LYS A 125;LEU A 114;GLU A 113;LEU A 115","None","1.14A","5nwwA-2eq9A:undetectable","5nwwA-2eq9A:5.83"],["5U63_A_ACTA405_0","THIOREDOXIN REDUCTASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"GLY A 329;LEU A 330;HIS A  23","None","0.71A","5u63A-2eq9A:27.0","5u63A-2eq9A:24.68"],["5U63_B_ACTB405_0","THIOREDOXIN REDUCTASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"GLY A 329;LEU A 330;HIS A  23","None","0.69A","5u63B-2eq9A:26.9","5u63B-2eq9A:24.68"],["5VW5_A_NCAA403_0","FERREDOXIN--NADP REDUCTASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"GLY A  20;GLY A 329;LEU A 330;ALA A 333","FAD A8482 (-3.5A);None;None;None","0.75A","5vw5A-2eq9A:2.2","5vw5A-2eq9A:21.68"],["5XOO_B_ADNB503_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",4,"LEU A 180;VAL A 263;GLU A 261;LEU A 254","None","1.03A","5xooB-2eq9A:undetectable","5xooB-2eq9A:10.17"],["5ZHM_B_SAMB301_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",6,"LEU A 106;GLY A 104;GLU A  39;LEU A  99;GLY A 101;GLY A 102","None;None;FAD A8482 (-2.7A);None;None;None","1.21A","5zhmB-2eq9A:undetectable","5zhmB-2eq9A:22.34"],["5ZHM_B_SAMB301_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",6,"LEU A 106;GLY A 104;GLU A  42;LEU A  99;GLY A 101;GLY A 102","None","1.50A","5zhmB-2eq9A:undetectable","5zhmB-2eq9A:22.34"],["6DWD_D_GLYD713_0","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",3,"ARG A 327;HIS A  23;ARG A  27","None","0.87A","6dwdD-2eq9A:undetectable","6dwdD-2eq9A:22.11"],["6GNF_C_QPSC602_2","-","2eq9","PYRUVATE DEHYDROGENASE COMPLEX, DIHYDROLIPOAMIDE DEHYDROGENASE E3 COMPONENT","Thermus thermophilus",5,"VAL A 298;ASP A 291;GLU A 150;PRO A 318;GLY A 313","None;None;None;None;FAD A8482 (-3.4A)","1.34A","6gnfC-2eq9A:undetectable","6gnfC-2eq9A:23.10"]]