SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 8 ILE A 210
PHE A 199
LEU A 202
HIS A 204
 None
 0.91A 2azxA-2eqxA:
undetectable		 2azxA-2eqxA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 LEU A 207
ILE A 211
LEU A 247
SER A 246
 None
 0.80A 2byoA-2eqxA:
undetectable		 2byoA-2eqxA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 9 LEU A 206
LEU A 207
ILE A 210
PHE A 199
LEU A 164
 None
 1.26A 2f78A-2eqxA:
undetectable		 2f78A-2eqxA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 9 LEU A 206
LEU A 207
ILE A 210
PHE A 199
LEU A 164
 None
 1.25A 2f78B-2eqxA:
undetectable		 2f78B-2eqxA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 9 LEU A 206
LEU A 207
ILE A 210
PHE A 199
LEU A 164
 None
 1.18A 2f7aA-2eqxA:
undetectable		 2f7aA-2eqxA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2eqx KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 9 LEU A 206
LEU A 207
ILE A 210
PHE A 199
LEU A 164
 None
 1.18A 2f7aB-2eqxA:
undetectable		 2f7aB-2eqxA:
19.49