SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 2eqy JUMONJI, AT RICH
INTERACTIVE DOMAIN
1B
(Mus
musculus) 		5 / 12 LEU A 130
PHE A 143
CYH A 147
ARG A 177
ILE A 178
 None
 1.31A 1skxA-2eqyA:
0.0		 1skxA-2eqyA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 2eqy JUMONJI, AT RICH
INTERACTIVE DOMAIN
1B
(Mus
musculus) 		5 / 12 VAL A 123
LEU A 130
PHE A 143
CYH A 147
ARG A 177
 None
 1.47A 1skxA-2eqyA:
0.0		 1skxA-2eqyA:
20.19