SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2erh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 6 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.18A 1kiaA-2erhA:
undetectable		 1kiaA-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 6 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.18A 1kiaB-2erhA:
undetectable		 1kiaB-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 7 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.17A 1kiaC-2erhA:
undetectable		 1kiaC-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 7 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.18A 1kiaD-2erhA:
undetectable		 1kiaD-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 6 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.15A 1nbhA-2erhA:
undetectable		 1nbhA-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 7 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.16A 1nbhB-2erhA:
undetectable		 1nbhB-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 6 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.16A 1nbhC-2erhA:
undetectable		 1nbhC-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2erh COLICIN E7 IMMUNITY
PROTEIN
COLICIN E7
(Escherichia
coli;
Escherichia
coli) 		4 / 7 TYR A  35
ASN A  26
ARG B 520
TYR A  55
 None
 1.14A 1nbhD-2erhA:
undetectable		 1nbhD-2erhA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 2erh COLICIN E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		4 / 7 LEU A  37
VAL A  36
GLU A  21
TYR A  10
 None
 1.12A 4lb2A-2erhA:
undetectable		 4lb2A-2erhA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 2erh COLICIN E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 9 ASP A  31
ALA A  28
VAL A  27
LYS A  24
GLU A  21
 None
 1.47A 4zbrA-2erhA:
2.9		 4zbrA-2erhA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2erh COLICIN E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		3 / 3 PHE A  41
ILE A  54
ASP A  31
 None
 0.77A 5cswA-2erhA:
undetectable		 5cswA-2erhA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2erh COLICIN E7
(Escherichia
coli) 		4 / 8 LEU B 543
GLU B 501
LEU B 484
ILE B 480
 None
 0.98A 5mzjA-2erhB:
undetectable		 5mzjA-2erhB:
14.02