SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2erv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  55
VAL A  93
TRP A  48
 None
 0.77A 1gmkA-2ervA:
undetectable
1gmkB-2ervA:
undetectable		 1gmkA-2ervA:
9.18
1gmkB-2ervA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  55
VAL A  93
TRP A  48
 None
 0.70A 1gmkC-2ervA:
undetectable
1gmkD-2ervA:
undetectable		 1gmkC-2ervA:
9.18
1gmkD-2ervA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 138
GLU A 140
ASP A 106
ASP A 137
 None
None
CA  A 195 ( 2.5A)
None
 1.22A 3mb5A-2ervA:
undetectable		 3mb5A-2ervA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		5 / 12 THR A  10
SER A 141
LEU A  98
VAL A  93
ALA A  86
 None
 1.46A 3u9fG-2ervA:
undetectable
3u9fH-2ervA:
undetectable		 3u9fG-2ervA:
20.71
3u9fH-2ervA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 147
PRO A 149
LYS A 113
 None
 1.50A 4duzL-2ervA:
0.0		 4duzL-2ervA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		3 / 3 LYS A  57
TRP A  48
SER A  89
 None
 1.04A 5nwwA-2ervA:
undetectable		 5nwwA-2ervA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 2erv HYPOTHETICAL PROTEIN
PAER03002360
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 106
LEU A  98
SER A 100
PHE A  88
 CA  A 195 ( 2.5A)
None
None
None
 1.17A 6ekuA-2ervA:
undetectable		 6ekuA-2ervA:
12.83