SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2es6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 2es6 VTS1P
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 447
LEU A 463
ILE A 518
LEU A 488
VAL A 493
 None
 1.15A 1hrkA-2es6A:
undetectable		 1hrkA-2es6A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2es6 VTS1P
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 447
LEU A 463
ILE A 518
LEU A 488
VAL A 493
 None
 1.14A 2hrcB-2es6A:
undetectable		 2hrcB-2es6A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2es6 VTS1P
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 460
ILE A 456
LEU A 472
LEU A 502
 None
 0.80A 2xfhA-2es6A:
undetectable		 2xfhA-2es6A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2es6 VTS1P
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 480
GLU A 489
LEU A 488
ALA A 471
LEU A 472
 None
 0.92A 4wg0H-2es6A:
undetectable
4wg0I-2es6A:
undetectable
4wg0J-2es6A:
undetectable		 4wg0H-2es6A:
11.11
4wg0I-2es6A:
11.11
4wg0J-2es6A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2es6 VTS1P
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 471
LEU A 472
GLU A 489
LEU A 488
LEU A 480
 None
 1.16A 4wg0K-2es6A:
undetectable
4wg0L-2es6A:
undetectable
4wg0M-2es6A:
undetectable		 4wg0K-2es6A:
11.11
4wg0L-2es6A:
11.11
4wg0M-2es6A:
11.11