SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2esb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		4 / 4 LEU A  27
ILE A  50
ILE A  86
ALA A  87
 None
 0.84A 2i30A-2esbA:
undetectable		 2i30A-2esbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		5 / 12 ILE A 174
ASN A 144
SER A 109
GLY A 146
TYR A 178
 None
None
EPE  A1002 (-4.3A)
None
None
 1.17A 2zw9A-2esbA:
undetectable		 2zw9A-2esbA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		4 / 8 GLY A  32
GLY A 107
ILE A 140
SER A  18
 None
EPE  A1002 (-4.3A)
None
None
 0.65A 3d41A-2esbA:
undetectable		 3d41A-2esbA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		4 / 6 LEU A 127
GLU A 155
ASN A 162
PHE A  83
 None
 1.42A 3i9jB-2esbA:
undetectable		 3i9jB-2esbA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		5 / 8 ASP A  84
PHE A  83
VAL A  71
SER A  74
GLN A 150
 None
 1.42A 4ac9C-2esbA:
undetectable		 4ac9C-2esbA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 2esb DUAL SPECIFICITY
PROTEIN PHOSPHATASE
18
(Homo
sapiens) 		4 / 8 ASN A  37
ALA A  34
LEU A 101
LEU A  20
 None
 0.98A 4jjkA-2esbA:
2.4		 4jjkA-2esbA:
16.82