SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2et6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 7 SER A 593
PHE A 580
ALA A 244
PHE A 242
 None
 1.14A 1fxvA-2et6A:
undetectable
1fxvB-2et6A:
undetectable		 1fxvA-2et6A:
16.67
1fxvB-2et6A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD6_0
(GRAMICIDIN A)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 4 VAL A 324
TRP A 372
ALA A 371
VAL A 350
 None
 1.49A 1gmkC-2et6A:
undetectable
1gmkD-2et6A:
undetectable		 1gmkC-2et6A:
5.28
1gmkD-2et6A:
5.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 GLU A 538
ILE A 494
THR A 453
LEU A 475
 None
 0.94A 1hmyA-2et6A:
4.7		 1hmyA-2et6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 LEU A 399
ILE A 449
PHE A 441
ILE A 386
 None
 0.84A 2azxA-2et6A:
undetectable		 2azxA-2et6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		6 / 12 LEU A 334
GLY A 329
ASP A 353
ASP A 377
ASN A 402
ALA A 403
 None
 1.26A 2bm9E-2et6A:
3.9		 2bm9E-2et6A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 6 ALA A 496
TYR A 459
ILE A 494
ILE A 458
 None
 1.27A 2dcfA-2et6A:
undetectable		 2dcfA-2et6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 7 ARG A 247
TRP A 552
GLU A 237
ALA A 190
 None
 1.11A 2ejgA-2et6A:
undetectable		 2ejgA-2et6A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 7 LEU A 524
ARG A 305
GLU A 273
ARG A 270
 None
 1.06A 2jn3A-2et6A:
undetectable		 2jn3A-2et6A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 LEU A  26
GLY A  17
ALA A  16
ILE A  12
ALA A  29
 None
 0.84A 2nmzB-2et6A:
undetectable		 2nmzB-2et6A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 6 TRP A 552
GLY A 457
GLY A 476
PHE A 235
 None
 1.04A 2qx6A-2et6A:
5.2
2qx6B-2et6A:
5.2		 2qx6A-2et6A:
17.73
2qx6B-2et6A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 ILE A 450
GLY A 529
LEU A 320
PHE A 342
 None
 0.93A 2vctC-2et6A:
undetectable		 2vctC-2et6A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 LEU A 222
SER A 225
PHE A   6
ALA A  33
 None
 0.96A 3ax9A-2et6A:
undetectable		 3ax9A-2et6A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 LEU A 475
THR A 539
VAL A 495
THR A 455
ILE A 458
 None
 1.20A 3bf1A-2et6A:
undetectable
3bf1B-2et6A:
undetectable		 3bf1A-2et6A:
17.54
3bf1B-2et6A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 329
GLY A 331
ASP A 377
VAL A 378
VAL A 425
 None
 0.93A 3dmfA-2et6A:
6.2		 3dmfA-2et6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 6 GLY A 252
TYR A 277
GLY A 548
ASN A 288
 None
 1.09A 3e9rA-2et6A:
undetectable		 3e9rA-2et6A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A  15
GLY A  17
LEU A  40
ASN A  74
VAL A  75
 None
 0.89A 3elwA-2et6A:
4.7		 3elwA-2et6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A  15
GLY A  17
LEU A  40
ASN A  74
VAL A  75
 None
 0.75A 3embA-2et6A:
4.9		 3embA-2et6A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 LEU A 154
GLY A 537
THR A 453
ILE A 458
 None
 0.81A 3jusA-2et6A:
undetectable		 3jusA-2et6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 LEU A 154
GLY A 537
THR A 453
ILE A 458
 None
 0.81A 3jusA-2et6A:
undetectable		 3jusA-2et6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 LEU A 154
GLY A 537
THR A 453
ILE A 458
 None
 0.71A 3jusB-2et6A:
undetectable		 3jusB-2et6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 PRO A 151
SER A 594
ASN A 157
 None
 0.84A 3lslG-2et6A:
undetectable		 3lslG-2et6A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 7 ILE A 191
VAL A 221
LEU A 224
SER A 225
 None
 0.58A 3r9vA-2et6A:
undetectable
3r9vB-2et6A:
undetectable		 3r9vA-2et6A:
18.45
3r9vB-2et6A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 ASN A 310
ALA A 309
LYS A 257
 None
 0.92A 3runA-2et6A:
undetectable		 3runA-2et6A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 9 LEU A 222
SER A 225
PHE A   6
VAL A  94
ALA A  33
 None
 1.49A 3unaA-2et6A:
0.0		 3unaA-2et6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 11 ASN A 401
GLY A 429
SER A 434
GLY A 476
MET A 107
 None
 1.38A 3v3oC-2et6A:
4.0		 3v3oC-2et6A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 548
GLY A 253
ASN A 295
GLU A 273
LEU A 524
 None
 1.12A 3vywA-2et6A:
4.0		 3vywA-2et6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		6 / 12 GLY A 548
GLY A 253
LEU A 286
GLU A 273
PHE A 256
LEU A 524
 None
 1.30A 3vywA-2et6A:
4.0		 3vywA-2et6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 9 ALA A 465
LEU A 177
LEU A 170
ASN A  97
ILE A 145
 None
 1.13A 3wdmA-2et6A:
3.2		 3wdmA-2et6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 9 ALA A 465
LEU A 177
LEU A 170
ASN A  97
ILE A 145
 None
 1.12A 3wdmC-2et6A:
3.2		 3wdmC-2et6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 10 ALA A 403
GLY A 429
LEU A 326
ASP A 377
ILE A 385
 None
 1.13A 3wdmD-2et6A:
2.6		 3wdmD-2et6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.86A 4ctjA-2et6A:
2.3		 4ctjA-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.90A 4ctjC-2et6A:
4.2		 4ctjC-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.88A 4ctkA-2et6A:
4.8		 4ctkA-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A  15
GLY A  17
LEU A  40
ASN A  74
VAL A 121
 None
 1.10A 4f84A-2et6A:
6.7		 4f84A-2et6A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 LEU A 224
GLU A 180
GLY A 233
PHE A 173
ILE A 191
 None
 1.16A 4hytA-2et6A:
3.9		 4hytA-2et6A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 LEU A 224
GLU A 180
GLY A 233
PHE A 173
ILE A 191
 None
 1.18A 4hytC-2et6A:
undetectable		 4hytC-2et6A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 ALA A 472
GLY A 457
SER A 456
ILE A 474
GLY A 476
 None
 1.09A 4obwA-2et6A:
5.4		 4obwA-2et6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 5 ARG A 554
ILE A 597
GLY A 602
LEU A 598
 None
 0.85A 5dzki-2et6A:
undetectable
5dzkj-2et6A:
undetectable
5dzkx-2et6A:
undetectable		 5dzki-2et6A:
16.14
5dzkj-2et6A:
16.14
5dzkx-2et6A:
1.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5e9qA-2et6A:
4.6		 5e9qA-2et6A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5ec8A-2et6A:
4.7		 5ec8A-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.88A 5ehgA-2et6A:
4.5		 5ehgA-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.91A 5ehgC-2et6A:
4.4		 5ehgC-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.87A 5eifA-2et6A:
undetectable		 5eifA-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5ekxB-2et6A:
4.1		 5ekxB-2et6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.90A 5ikmA-2et6A:
undetectable		 5ikmA-2et6A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 GLY A 460
GLN A 464
LYS A 179
 None
 0.94A 5imsB-2et6A:
2.7		 5imsB-2et6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 GLY A  17
ASP A  39
ASN A  74
 None
 0.55A 5jglA-2et6A:
5.7		 5jglA-2et6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 ASP A 279
ASN A 586
GLN A 553
 None
 0.65A 5k7uA-2et6A:
undetectable		 5k7uA-2et6A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.88A 5kqrA-2et6A:
4.9		 5kqrA-2et6A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5kqsA-2et6A:
2.3		 5kqsA-2et6A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 8 VAL A 389
ILE A 386
ALA A 437
VAL A 325
VAL A 324
 None
 1.45A 5l94A-2et6A:
undetectable		 5l94A-2et6A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.91A 5m5bA-2et6A:
2.3		 5m5bA-2et6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.90A 5njvA-2et6A:
5.0		 5njvA-2et6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5njvB-2et6A:
4.8		 5njvB-2et6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5njvC-2et6A:
undetectable		 5njvC-2et6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 PHE A 173
LEU A 171
SER A 468
GLY A 457
GLY A 473
 None
 1.24A 5o4yD-2et6A:
undetectable
5o4yE-2et6A:
undetectable		 5o4yD-2et6A:
1.67
5o4yE-2et6A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 10 ALA A 522
LEU A 525
VAL A 526
GLU A 337
ILE A 327
 None
 0.82A 5v02B-2et6A:
undetectable
5v02R-2et6A:
undetectable		 5v02B-2et6A:
9.95
5v02R-2et6A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.88A 5vimA-2et6A:
3.3		 5vimA-2et6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.90A 5vimB-2et6A:
4.8		 5vimB-2et6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.89A 5wz2A-2et6A:
undetectable		 5wz2A-2et6A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.87A 5wz2B-2et6A:
undetectable		 5wz2B-2et6A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 GLY A 333
GLY A 404
GLY A 329
GLY A 335
ILE A 405
 None
 0.86A 5wz2C-2et6A:
undetectable		 5wz2C-2et6A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 8 ILE A 547
PHE A 262
ASN A 310
PRO A 523
 None
 1.15A 5x23A-2et6A:
undetectable		 5x23A-2et6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 ALA A 347
VAL A 389
TYR A 393
 None
 0.31A 5zmqH-2et6A:
undetectable		 5zmqH-2et6A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		3 / 3 TYR A 163
ALA A 169
LEU A 170
 None
 0.65A 6ag0C-2et6A:
undetectable		 6ag0C-2et6A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		5 / 12 LEU A 524
VAL A 495
LEU A 399
THR A 430
LEU A 433
 None
 1.10A 6b54A-2et6A:
1.6		 6b54A-2et6A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 9 VAL A  11
HIS A  93
LEU A  26
VAL A  62
 None
 0.92A 6c2mD-2et6A:
undetectable		 6c2mD-2et6A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 4 HIS A 122
LEU A  20
TYR A  24
GLY A  15
 None
 1.42A 6n91A-2et6A:
1.5		 6n91A-2et6A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 4 HIS A 426
LEU A 334
TYR A 338
GLY A 329
 None
 1.45A 6n91A-2et6A:
1.5		 6n91A-2et6A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 4 HIS A 122
LEU A  20
TYR A  24
GLY A  15
 None
 1.43A 6n91B-2et6A:
undetectable		 6n91B-2et6A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2et6 (3R)-HYDROXYACYL-COA
DEHYDROGENASE
(Candida
tropicalis) 		4 / 4 HIS A 426
LEU A 334
TYR A 338
GLY A 329
 None
 1.45A 6n91B-2et6A:
undetectable		 6n91B-2et6A:
10.07