SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ALA A 139
VAL A 137
TRP A   4
 None
 0.99A 1gmkC-2eveA:
undetectable
1gmkD-2eveA:
undetectable		 1gmkC-2eveA:
31.25
1gmkD-2eveA:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 SER A  14
HIS A  81
ASP A  77
 None
 0.76A 2wa2B-2eveA:
undetectable		 2wa2B-2eveA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 GLY A  58
PHE A 105
GLU A  56
LEU A 114
ILE A 145
 None
 1.35A 3kvrB-2eveA:
undetectable		 3kvrB-2eveA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ASP A  72
ARG A  25
ASP A  77
 None
 0.76A 4fp9D-2eveA:
undetectable		 4fp9D-2eveA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 109
PHE A  48
ILE A  62
LEU A 150
 None
 0.86A 5eseA-2eveA:
undetectable		 5eseA-2eveA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TRP A 142
GLU A  46
ASP A 103
 None
 1.06A 5gqbA-2eveA:
undetectable		 5gqbA-2eveA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2eve HYPOTHETICAL PROTEIN
PSPTO5229
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A  66
VAL A 102
ILE A  59
PHE A  48
 None
 1.03A 5jw1B-2eveA:
undetectable		 5jw1B-2eveA:
14.77