SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2evr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 5 ARG A 196
ALA A 210
ASP A 202
GLY A 208
 None
 1.19A 1e7cA-2evrA:
undetectable		 1e7cA-2evrA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 12 ASP A 164
THR A 104
ILE A 101
SER A 136
PHE A 134
 None
 1.36A 1xoqA-2evrA:
undetectable		 1xoqA-2evrA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 12 ASP A 164
THR A 104
ILE A 101
SER A 136
PHE A 134
 None
 1.38A 1xoqB-2evrA:
undetectable		 1xoqB-2evrA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 8 TYR A 146
TYR A  64
GLY A 117
THR A  36
ALA A  35
 None
 1.23A 2a1hA-2evrA:
undetectable
2a1hB-2evrA:
undetectable		 2a1hA-2evrA:
20.05
2a1hB-2evrA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 8 TYR A 114
ASP A 125
SER A 127
HIS A 176
 None
 1.34A 2bteA-2evrA:
undetectable		 2bteA-2evrA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 10 TYR A  64
GLY A 117
THR A  36
ALA A  35
TYR A 146
 None
 1.25A 2coiA-2evrA:
undetectable
2coiB-2evrA:
undetectable		 2coiA-2evrA:
20.85
2coiB-2evrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 10 TYR A 146
TYR A  64
GLY A 117
THR A  36
ALA A  35
 None
 1.22A 2coiA-2evrA:
undetectable
2coiB-2evrA:
undetectable		 2coiA-2evrA:
20.85
2coiB-2evrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 11 TYR A  64
GLY A 117
THR A  36
ALA A  35
TYR A 146
 None
 1.20A 2cojA-2evrA:
undetectable
2cojB-2evrA:
undetectable		 2cojA-2evrA:
20.85
2cojB-2evrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 9 TYR A 146
TYR A  64
GLY A 117
THR A  36
ALA A  35
 None
 1.20A 2cojA-2evrA:
undetectable
2cojB-2evrA:
undetectable		 2cojA-2evrA:
20.85
2cojB-2evrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 6 PHE A 167
THR A 152
VAL A 225
ALA A 222
 None
 1.06A 2e1qA-2evrA:
undetectable		 2e1qA-2evrA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 12 PHE A 226
GLY A 223
THR A 152
ASP A 164
ILE A 157
 None
 1.24A 3iv6B-2evrA:
undetectable		 3iv6B-2evrA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 6 GLY A 163
TYR A 186
ALA A 162
TYR A 180
 None
 1.00A 4ae1A-2evrA:
undetectable		 4ae1A-2evrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 8 GLY A 178
GLY A 163
LEU A  97
VAL A 100
 None
 0.93A 4fgzA-2evrA:
undetectable		 4fgzA-2evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_I_MTXI301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		5 / 9 PHE A  26
CYH A  60
LEU A  59
GLU A  61
HIS A  43
 None
 1.27A 4l8wI-2evrA:
undetectable		 4l8wI-2evrA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 7 PHE A 134
SER A 136
ALA A  98
LEU A  97
 None
 1.05A 4xk8A-2evrA:
undetectable		 4xk8A-2evrA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 6 ILE A 155
VAL A 166
ASP A 164
ALA A 222
 None
 0.72A 5cu6A-2evrA:
undetectable		 5cu6A-2evrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 7 VAL A 225
THR A 152
LEU A 179
VAL A 177
 None
 1.04A 5e4dA-2evrA:
undetectable
5e4dB-2evrA:
undetectable		 5e4dA-2evrA:
22.57
5e4dB-2evrA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 4 ARG A 196
ILE A 201
TYR A 185
ILE A 203
 None
 1.43A 5odhG-2evrA:
undetectable		 5odhG-2evrA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)
(Nostoc
punctiforme) 		4 / 7 ILE A 155
VAL A 166
ASP A 164
ALA A 222
 None
 0.75A 5ospA-2evrA:
undetectable		 5ospA-2evrA:
20.22