SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2evv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		3 / 3 ALA A  53
VAL A  73
TRP A  72
 None
 0.97A 1c4dA-2evvA:
undetectable
1c4dB-2evvA:
undetectable		 1c4dA-2evvA:
5.75
1c4dB-2evvA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_B_PE2B2_1
(THYMIDINE KINASE)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		5 / 12 HIS A 160
ILE A 170
TYR A 141
MET A   1
GLU A  55
 None
 1.44A 1ki3B-2evvA:
0.0		 1ki3B-2evvA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		4 / 6 ASN A  98
ILE A  93
GLN A  95
THR A  36
 None
 1.15A 2hkkA-2evvA:
undetectable		 2hkkA-2evvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		5 / 12 ILE A 125
GLY A  22
LEU A  29
ASN A  30
TYR A 124
 None
 1.25A 2zw9A-2evvA:
undetectable		 2zw9A-2evvA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		5 / 12 GLY A  22
LYS A  19
PHE A  28
ASP A  17
GLY A 126
 None
 1.37A 3ps9A-2evvA:
undetectable		 3ps9A-2evvA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 2evv HYPOTHETICAL PROTEIN
HP0218
(Helicobacter
pylori) 		5 / 12 ALA A  18
ASP A  17
LEU A  16
MET A 128
PRO A  39
 None
 1.34A 4xi3A-2evvA:
undetectable		 4xi3A-2evvA:
20.97