SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ew0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ew0 HYPOTHETICAL PROTEIN
ACIAD0353
(Acinetobacter
sp.
ADP1) 		4 / 8 PHE A  22
ILE A  41
PHE A  21
GLY A 126
 None
 0.99A 2qwxA-2ew0A:
undetectable
2qwxB-2ew0A:
undetectable		 2qwxA-2ew0A:
19.51
2qwxB-2ew0A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 2ew0 HYPOTHETICAL PROTEIN
ACIAD0353
(Acinetobacter
sp.
ADP1) 		4 / 8 VAL A 100
VAL A  96
ASP A 150
ARG A 162
 None
 1.08A 3uy4A-2ew0A:
undetectable		 3uy4A-2ew0A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ew0 HYPOTHETICAL PROTEIN
ACIAD0353
(Acinetobacter
sp.
ADP1) 		4 / 4 PRO A  14
LEU A 145
ILE A 170
ARG A 174
 None
 1.35A 3w1wA-2ew0A:
undetectable		 3w1wA-2ew0A:
20.83