SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ewy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 9 LEU A 137
LEU A  32
ILE A 103
VAL A 113
PHE A  54
 None
 1.42A 1gx8A-2ewyA:
undetectable		 1gx8A-2ewyA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 LEU A 137
PHE A 153
ARG A 363
 None
 0.88A 1xdkB-2ewyA:
undetectable		 1xdkB-2ewyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 11 TYR A 203
GLY A 365
ILE A 382
TRP A 202
ALA A 367
 None
 1.42A 2a58A-2ewyA:
undetectable
2a58E-2ewyA:
undetectable		 2a58A-2ewyA:
18.80
2a58E-2ewyA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A  46
ASP A  48
GLY A  50
ASN A  53
ILE A 134
 None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
None
 0.78A 2f80B-2ewyA:
6.4		 2f80B-2ewyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A  46
ASP A  48
GLY A  50
ASN A  53
ILE A 134
 None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
None
 0.76A 2q64A-2ewyA:
6.7		 2q64A-2ewyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A  46
ASP A  48
GLY A  50
ASN A  53
ILE A 134
 None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
None
 0.78A 2q64B-2ewyA:
6.6		 2q64B-2ewyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A  46
ASP A  48
GLY A  50
ASN A  53
ILE A 134
 None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
None
 0.80A 2qakA-2ewyA:
6.6		 2qakA-2ewyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A  46
ASP A  48
GLY A  50
ASN A  53
ILE A 134
 None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
None
 0.86A 2qakB-2ewyA:
6.6		 2qakB-2ewyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		6 / 12 ASP A  48
GLY A  50
SER A  51
TYR A  87
ASP A 241
GLY A 243
 DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
DBO  A1001 (-4.1A)
DBO  A1001 (-3.8A)
DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
 0.39A 2v0zC-2ewyA:
35.1		 2v0zC-2ewyA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		6 / 12 ASP A 241
GLY A 243
VAL A 344
ASP A  48
GLY A  50
SER A  52
 DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
 1.19A 2v0zC-2ewyA:
35.1		 2v0zC-2ewyA:
27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		6 / 12 ASP A 241
GLY A 243
VAL A 344
ASP A  48
GLY A  50
SER A  52
 DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
None
DBO  A1001 (-2.7A)
DBO  A1001 (-3.7A)
None
 1.18A 2v0zO-2ewyA:
35.4		 2v0zO-2ewyA:
27.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 5 LEU A  46
ASP A  48
ILE A 134
GLY A 243
 None
DBO  A1001 (-2.7A)
None
DBO  A1001 (-4.2A)
 0.31A 3bufA-2ewyA:
51.6		 3bufA-2ewyA:
52.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 LEU A 149
GLU A  98
ILE A 115
 None
 0.59A 3czhA-2ewyA:
undetectable		 3czhA-2ewyA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ASP A 241
GLY A 243
LEU A  46
ASP A  48
SER A  52
 DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
None
DBO  A1001 (-2.7A)
None
 0.86A 3d91A-2ewyA:
17.1		 3d91A-2ewyA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ASP A 241
GLY A 243
LEU A  46
ASP A  48
SER A  52
 DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
None
DBO  A1001 (-2.7A)
None
 0.89A 3d91B-2ewyA:
35.1		 3d91B-2ewyA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ASP A 241
GLY A 243
VAL A 344
LEU A  46
ASP A  48
 DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
None
None
DBO  A1001 (-2.7A)
 1.01A 3d91B-2ewyA:
35.1		 3d91B-2ewyA:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 6 PHE A  68
TYR A  76
THR A 117
VAL A  56
 None
 1.09A 3lb3A-2ewyA:
undetectable		 3lb3A-2ewyA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 6 PHE A  68
TYR A  76
THR A 117
VAL A  56
 None
 1.19A 3lb3B-2ewyA:
undetectable		 3lb3B-2ewyA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 8 LEU A 156
SER A 155
LEU A 187
ARG A 359
ILE A 162
 None
 1.20A 3ln1A-2ewyA:
undetectable		 3ln1A-2ewyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 7 LEU A 156
SER A 155
LEU A 187
ARG A 359
ILE A 162
 None
 1.22A 3ln1B-2ewyA:
undetectable		 3ln1B-2ewyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 LEU A 135
PHE A  54
VAL A 113
ALA A 160
PHE A 111
 None
 1.37A 3nuvA-2ewyA:
undetectable		 3nuvA-2ewyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 8 LEU A 137
ALA A 140
THR A 151
GLY A 190
 None
 0.88A 3ny4A-2ewyA:
undetectable		 3ny4A-2ewyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 TYR A  31
GLY A  24
ASP A  25
 None
 0.71A 3ou6C-2ewyA:
undetectable		 3ou6C-2ewyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 8 GLY A  50
SER A  51
TYR A  87
ASP A 241
THR A 245
 DBO  A1001 (-3.7A)
DBO  A1001 (-4.1A)
DBO  A1001 (-3.8A)
DBO  A1001 (-3.2A)
DBO  A1001 (-3.8A)
 0.29A 3pwwA-2ewyA:
5.1		 3pwwA-2ewyA:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 11 TYR A 318
GLY A 335
GLY A  27
SER A  26
ALA A 173
 None
 1.13A 3sufC-2ewyA:
undetectable		 3sufC-2ewyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 11 PHE A  54
VAL A 113
PHE A 152
ILE A  36
GLY A  37
 None
 1.02A 3t3rA-2ewyA:
undetectable		 3t3rA-2ewyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 10 PHE A  54
VAL A 113
PHE A 152
ILE A  36
GLY A  37
 None
 1.02A 3t3rD-2ewyA:
undetectable		 3t3rD-2ewyA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ILE A 239
ASP A 241
GLY A 243
ASP A  48
ILE A 134
 None
DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
DBO  A1001 (-2.7A)
None
 0.77A 3tneA-2ewyA:
33.1		 3tneA-2ewyA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 6 SER A  51
TYR A  87
THR A 244
THR A 245
 DBO  A1001 (-4.1A)
DBO  A1001 (-3.8A)
DBO  A1001 (-3.8A)
DBO  A1001 (-3.8A)
 0.35A 3tneA-2ewyA:
33.1		 3tneA-2ewyA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ILE A 239
ASP A 241
GLY A 243
ASP A  48
ILE A 134
 None
DBO  A1001 (-3.2A)
DBO  A1001 (-4.2A)
DBO  A1001 (-2.7A)
None
 0.77A 3tneB-2ewyA:
33.0		 3tneB-2ewyA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 7 SER A  51
TYR A  87
ILE A 134
THR A 244
THR A 245
 DBO  A1001 (-4.1A)
DBO  A1001 (-3.8A)
None
DBO  A1001 (-3.8A)
DBO  A1001 (-3.8A)
 0.54A 3tneB-2ewyA:
33.0		 3tneB-2ewyA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 8 LEU A 126
ASN A 132
GLY A 133
ILE A 134
 None
 0.91A 3wxoA-2ewyA:
undetectable		 3wxoA-2ewyA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 ILE A 345
LEU A 249
PRO A 250
VAL A 253
ILE A 296
 None
 1.02A 4m2xG-2ewyA:
undetectable		 4m2xG-2ewyA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 ASP A 241
ASP A  48
ASN A  53
 DBO  A1001 (-3.2A)
DBO  A1001 (-2.7A)
None
 0.61A 4q5mA-2ewyA:
9.2		 4q5mA-2ewyA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 8 PHE A 124
PHE A 125
TRP A 131
ILE A 115
 DBO  A1001 (-4.2A)
None
None
None
 0.95A 4qoiA-2ewyA:
undetectable
4qoiB-2ewyA:
undetectable		 4qoiA-2ewyA:
22.28
4qoiB-2ewyA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 SER A  78
TYR A  76
ASP A  82
 None
 0.89A 4rp8C-2ewyA:
undetectable		 4rp8C-2ewyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		6 / 12 GLY A 243
GLY A  50
GLY A 136
ASN A  53
ALA A 347
THR A 348
 DBO  A1001 (-4.2A)
DBO  A1001 (-3.7A)
None
None
None
None
 1.14A 4uckA-2ewyA:
undetectable		 4uckA-2ewyA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 12 GLY A  50
GLY A 136
ASN A  53
ALA A 347
THR A 348
 DBO  A1001 (-3.7A)
None
None
None
None
 1.13A 4uckB-2ewyA:
undetectable		 4uckB-2ewyA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		5 / 11 LEU A 343
LEU A 300
LEU A 219
VAL A 349
ILE A 296
 None
 1.19A 4x20D-2ewyA:
undetectable		 4x20D-2ewyA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 7 ILE A  45
ILE A  64
THR A 117
ILE A 118
 None
 0.71A 5fukA-2ewyA:
undetectable
5fukB-2ewyA:
undetectable		 5fukA-2ewyA:
21.68
5fukB-2ewyA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		4 / 7 ASP A  48
THR A  49
VAL A  85
TYR A  87
 DBO  A1001 (-2.7A)
None
None
DBO  A1001 (-3.8A)
 0.92A 5ov9A-2ewyA:
undetectable		 5ov9A-2ewyA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 GLY A  50
VAL A 355
MET A 168
 DBO  A1001 (-3.7A)
None
None
 0.65A 5ycpA-2ewyA:
undetectable		 5ycpA-2ewyA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ewy BETA-SECRETASE 2
(Homo
sapiens) 		3 / 3 GLY A 243
VAL A 355
MET A 168
 DBO  A1001 (-4.2A)
None
None
 0.59A 5ycpA-2ewyA:
undetectable		 5ycpA-2ewyA:
13.48