SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ex3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_D_TFPD207_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2ex3	DNA TERMINAL PROTEIN (Bacillus virus phi29)	4 / 8	SER B 189 LEU B 182 PHE B 215 LEU B 248	None	0.89A	1wrlC-2ex3B: undetectable 1wrlD-2ex3B: undetectable	1wrlC-2ex3B: 19.07 1wrlD-2ex3B: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB501_2 (PHOSPHOLIPASE A2)	2ex3	DNA TERMINAL PROTEIN (Bacillus virus phi29)	5 / 11	VAL B 105 LEU B 104 SER B 165 THR B 98 LYS B 90	None	1.20A	3bjwB-2ex3B: undetectable	3bjwB-2ex3B: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_E_SVRE503_1 (PHOSPHOLIPASE A2)	2ex3	DNA TERMINAL PROTEIN (Bacillus virus phi29)	5 / 11	VAL B 105 LEU B 104 SER B 165 THR B 98 LYS B 90	None	1.27A	3bjwE-2ex3B: undetectable	3bjwE-2ex3B: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF502_3 (PHOSPHOLIPASE A2)	2ex3	DNA TERMINAL PROTEIN (Bacillus virus phi29)	5 / 12	VAL B 105 LEU B 104 SER B 165 THR B 98 LYS B 90	None	1.21A	3bjwF-2ex3B: undetectable	3bjwF-2ex3B: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_3 (PHOSPHOLIPASE A2)	2ex3	DNA TERMINAL PROTEIN (Bacillus virus phi29)	3 / 3	PRO B 145 PHE B 148 LYS B 99	None	1.21A	3bjwG-2ex3B: undetectable	3bjwG-2ex3B: 14.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_D_TFPD207_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2ex3","DNA TERMINAL PROTEIN","Bacillus virus phi29",4,"SER B 189;LEU B 182;PHE B 215;LEU B 248","None","0.89A","1wrlC-2ex3B:undetectable;1wrlD-2ex3B:undetectable","1wrlC-2ex3B:19.07;1wrlD-2ex3B:19.07"],["3BJW_B_SVRB501_2","PHOSPHOLIPASE A2","2ex3","DNA TERMINAL PROTEIN","Bacillus virus phi29",5,"VAL B 105;LEU B 104;SER B 165;THR B  98;LYS B  90","None","1.20A","3bjwB-2ex3B:undetectable","3bjwB-2ex3B:14.72"],["3BJW_E_SVRE503_1","PHOSPHOLIPASE A2","2ex3","DNA TERMINAL PROTEIN","Bacillus virus phi29",5,"VAL B 105;LEU B 104;SER B 165;THR B  98;LYS B  90","None","1.27A","3bjwE-2ex3B:undetectable","3bjwE-2ex3B:14.72"],["3BJW_F_SVRF502_3","PHOSPHOLIPASE A2","2ex3","DNA TERMINAL PROTEIN","Bacillus virus phi29",5,"VAL B 105;LEU B 104;SER B 165;THR B  98;LYS B  90","None","1.21A","3bjwF-2ex3B:undetectable","3bjwF-2ex3B:14.72"],["3BJW_G_SVRG506_3","PHOSPHOLIPASE A2","2ex3","DNA TERMINAL PROTEIN","Bacillus virus phi29",3,"PRO B 145;PHE B 148;LYS B  99","None","1.21A","3bjwG-2ex3B:undetectable","3bjwG-2ex3B:14.72"]]