SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		3 / 3 VAL A  37
VAL A  51
TRP A  15
 None
 0.95A 1bdwA-2eyyA:
undetectable
1bdwB-2eyyA:
undetectable		 1bdwA-2eyyA:
4.41
1bdwB-2eyyA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.05A 3kvvA-2eyyA:
undetectable		 3kvvA-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.05A 3kvvB-2eyyA:
undetectable		 3kvvB-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.03A 3kvvC-2eyyA:
undetectable		 3kvvC-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.02A 3kvvD-2eyyA:
undetectable		 3kvvD-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.07A 3kvvE-2eyyA:
undetectable		 3kvvE-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.04A 3kvvF-2eyyA:
undetectable		 3kvvF-2eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 7 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.05A 4e1vB-2eyyA:
undetectable		 4e1vB-2eyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 6 GLY A 126
GLN A 123
ILE A 128
VAL A 127
 None
 1.07A 4e1vF-2eyyA:
undetectable		 4e1vF-2eyyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 5 PRO A 165
ASP A 163
ASN A 171
ILE A 182
 None
 1.42A 4hytA-2eyyA:
undetectable		 4hytA-2eyyA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2eyy V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 4 PRO A 165
ASP A 163
ASN A 171
ILE A 182
 None
 1.42A 4hytC-2eyyA:
0.0		 4hytC-2eyyA:
11.54