SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2eyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2eyz V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		4 / 7 ARG A  56
SER A  58
SER A  55
GLU A  53
 None
 1.28A 2c8aA-2eyzA:
undetectable		 2c8aA-2eyzA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2eyz V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		5 / 12 LEU A 100
PHE A 103
ILE A  62
GLY A  90
ILE A 115
 None
 1.03A 4nkxD-2eyzA:
undetectable		 4nkxD-2eyzA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 2eyz V-CRK SARCOMA VIRUS
CT10 ONCOGENE
HOMOLOG ISOFORM A
(Homo
sapiens) 		5 / 9 SER A  43
SER A  83
GLY A  81
SER A  85
GLY A  66
 None
 1.20A 6bklE-2eyzA:
undetectable
6bklF-2eyzA:
undetectable
6bklG-2eyzA:
undetectable
6bklH-2eyzA:
undetectable		 6bklE-2eyzA:
6.12
6bklF-2eyzA:
6.12
6bklG-2eyzA:
6.12
6bklH-2eyzA:
6.12