SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 5 THR A 133
THR A 132
GLU A 358
THR A 357
 None
 1.08A 1d4fB-2f00A:
2.0		 1d4fB-2f00A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.18A 1ddrB-2f00A:
undetectable		 1ddrB-2f00A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.12A 1dyiB-2f00A:
undetectable		 1dyiB-2f00A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.14A 1jolA-2f00A:
3.3		 1jolA-2f00A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.12A 1jolB-2f00A:
3.2		 1jolB-2f00A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 LEU A  51
ASP A  50
ILE A  27
GLY A  26
HIS A  23
 None
 1.17A 1s9aA-2f00A:
undetectable		 1s9aA-2f00A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 LEU A  51
ASP A  50
ILE A  27
GLY A  26
HIS A  23
 None
 1.17A 1s9aB-2f00A:
undetectable		 1s9aB-2f00A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		3 / 3 LEU A 146
HIS A 120
ILE A 122
 None
 0.59A 1s9pB-2f00A:
undetectable		 1s9pB-2f00A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		6 / 10 LEU A 112
ILE A  27
GLY A  28
GLY A  29
VAL A 151
ILE A  35
 None
 1.26A 1sdtA-2f00A:
undetectable		 1sdtA-2f00A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 8 LEU A 185
ARG A 119
GLY A  34
MET A  32
 None
 0.77A 2po5A-2f00A:
3.3		 2po5A-2f00A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 8 LEU A 185
ARG A 119
GLY A  34
MET A  32
 None
 0.80A 2po5B-2f00A:
2.5		 2po5B-2f00A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 9 LEU A 112
ILE A  27
GLY A  29
VAL A 151
ILE A  35
 None
 1.19A 2r5qA-2f00A:
undetectable		 2r5qA-2f00A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 TYR A 141
PRO A 187
ALA A 300
ALA A 302
THR A 248
 None
 1.29A 2x2nA-2f00A:
undetectable		 2x2nA-2f00A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 TYR A 141
PRO A 187
ALA A 300
ALA A 302
THR A 248
 None
 1.24A 2x2nB-2f00A:
undetectable		 2x2nB-2f00A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 TYR A 141
PRO A 187
ALA A 300
ALA A 302
THR A 248
 None
 1.26A 2x2nC-2f00A:
undetectable		 2x2nC-2f00A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.23A 2zzaA-2f00A:
3.2		 2zzaA-2f00A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.23A 2zzaB-2f00A:
3.2		 2zzaB-2f00A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 5 PRO A 234
VAL A 235
THR A 133
GLY A 129
 None
 1.14A 3elzB-2f00A:
2.4		 3elzB-2f00A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 LEU A  51
ASP A  50
ILE A  27
GLY A  26
HIS A  23
 None
 1.20A 3hgiA-2f00A:
undetectable		 3hgiA-2f00A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 10 ILE A  27
GLU A  94
ASN A  70
ILE A  67
ALA A  65
 None
 1.43A 3u6tA-2f00A:
undetectable		 3u6tA-2f00A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		3 / 3 TYR A 263
ARG A 283
HIS A 271
 None
 1.02A 4fubA-2f00A:
undetectable		 4fubA-2f00A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.13A 4i1nA-2f00A:
3.3		 4i1nA-2f00A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 10 ALA A 317
LEU A 318
ALA A 294
ALA A 299
THR A 133
 None
 1.06A 4j14A-2f00A:
undetectable		 4j14A-2f00A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		3 / 3 HIS A 271
VAL A 301
LEU A 318
 None
 0.77A 4m2vA-2f00A:
undetectable		 4m2vA-2f00A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.20A 4p66A-2f00A:
undetectable		 4p66A-2f00A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A  22
ALA A  79
THR A  66
ILE A  67
ILE A  46
 None
 1.11A 4ptjA-2f00A:
2.5		 4ptjA-2f00A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.16A 4qleB-2f00A:
2.3		 4qleB-2f00A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.18A 4qlfA-2f00A:
2.5		 4qlfA-2f00A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.19A 4rgcA-2f00A:
3.3		 4rgcA-2f00A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 VAL A 151
PHE A 321
GLY A 129
ASN A 293
GLU A 174
 None
 1.32A 4zvmA-2f00A:
2.4
4zvmB-2f00A:
3.8		 4zvmA-2f00A:
19.24
4zvmB-2f00A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.16A 5e8qB-2f00A:
2.5		 5e8qB-2f00A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.13A 5hi6B-2f00A:
2.9		 5hi6B-2f00A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 10 ALA A 304
THR A 305
GLU A 306
ALA A 297
THR A 133
 None
 1.03A 5lf3H-2f00A:
undetectable
5lf3I-2f00A:
undetectable		 5lf3H-2f00A:
20.56
5lf3I-2f00A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 10 ALA A 304
THR A 305
GLU A 306
ALA A 297
THR A 133
 None
 1.03A 5lf3V-2f00A:
undetectable
5lf3W-2f00A:
undetectable		 5lf3V-2f00A:
20.56
5lf3W-2f00A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ALA A 304
THR A 305
GLU A 306
ALA A 297
THR A 133
 None
 1.02A 5lf7H-2f00A:
undetectable
5lf7I-2f00A:
undetectable		 5lf7H-2f00A:
20.56
5lf7I-2f00A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 11 ALA A 304
THR A 305
GLU A 306
ALA A 297
THR A 133
 None
 1.02A 5lf7V-2f00A:
undetectable
5lf7W-2f00A:
undetectable		 5lf7V-2f00A:
20.56
5lf7W-2f00A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 4 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.21A 5n0rA-2f00A:
2.0		 5n0rA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 4 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.21A 5n0sA-2f00A:
2.1		 5n0sA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 5 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.22A 5n0tA-2f00A:
2.2		 5n0tA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 4 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.23A 5n0wA-2f00A:
2.2		 5n0wA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 5 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.26A 5n0wB-2f00A:
2.3		 5n0wB-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 4 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.20A 5n0xA-2f00A:
2.2		 5n0xA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		4 / 5 SER A 138
ALA A 135
GLN A 322
THR A 324
 None
 1.21A 5n4iA-2f00A:
2.1		 5n4iA-2f00A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE
(Escherichia
coli) 		5 / 12 ILE A 140
ALA A 302
LEU A 274
LEU A 286
THR A 305
 None
 1.14A 5ujxB-2f00A:
3.4		 5ujxB-2f00A:
17.41