SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A  83
VAL A  86
LEU A  90
 HIS  A 152 (-3.7A)
None
None
 0.53A 1mz9B-2f06A:
undetectable		 1mz9B-2f06A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 VAL A 130
GLU A 127
LEU A 125
PHE A  89
 None
 1.00A 1s8fB-2f06A:
undetectable		 1s8fB-2f06A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A  31
LEU A  24
LEU A   6
LEU A  45
 None
 1.05A 2ab2B-2f06A:
undetectable		 2ab2B-2f06A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  46
SER A   7
TYR A 101
 None
 0.98A 2q2hA-2f06A:
undetectable
2q2hB-2f06A:
undetectable		 2q2hA-2f06A:
24.52
2q2hB-2f06A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 ALA A  82
VAL A 130
VAL A  86
LEU A  83
 HIS  A 152 (-3.8A)
None
None
HIS  A 152 (-3.7A)
 0.83A 3o14A-2f06A:
undetectable		 3o14A-2f06A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A  90
LEU A  87
LEU A  83
ILE A  74
ILE A  97
 None
None
HIS  A 152 (-3.7A)
None
None
 0.95A 4a7aB-2f06A:
undetectable		 4a7aB-2f06A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2f06 CONSERVED
HYPOTHETICAL PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS A  54
ALA A  55
LEU A  59
LEU A   6
 None
 0.51A 4po0A-2f06A:
undetectable		 4po0A-2f06A:
12.74