SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 6 TRP A  99
LYS A 126
TRP A 133
ASN A 150
 None
 0.67A 1dedA-2f15A:
8.2		 1dedA-2f15A:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.21A 2obvA-2f15A:
undetectable		 2obvA-2f15A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.16A 2p02A-2f15A:
undetectable		 2p02A-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.19A 4kttA-2f15A:
undetectable		 4kttA-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.20A 4kttC-2f15A:
undetectable		 4kttC-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.17A 4ndnA-2f15A:
undetectable		 4ndnA-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.18A 5a1iA-2f15A:
undetectable		 5a1iA-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.22A 6fbnB-2f15A:
undetectable		 6fbnB-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.18A 6fboA-2f15A:
undetectable		 6fboA-2f15A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.15A 6fcbA-2f15A:
undetectable		 6fcbA-2f15A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 8 HIS A 123
PRO A 119
SER A  93
SER A 100
 None
 1.17A 6fcdA-2f15A:
undetectable		 6fcdA-2f15A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2f15 5'-AMP-ACTIVATED
PROTEIN KINASE,
BETA-2 SUBUNIT
(Homo
sapiens) 		4 / 7 ASP A 111
GLU A  85
ASP A 136
GLU A 139
 None
 1.30A 6mn5E-2f15A:
undetectable		 6mn5E-2f15A:
23.76