SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A131_2 (FATTY ACID-BINDING PROTEIN, LIVER)	2f1m	ACRIFLAVINE RESISTANCE PROTEIN A (Escherichia coli)	4 / 6	LEU A 246 GLN A 207 ILE A 212 PHE A 280	None	0.78A	2jn3A-2f1mA: undetectable	2jn3A-2f1mA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B301_1 (THIOPURINE S-METHYLTRANSFERASE)	2f1m	ACRIFLAVINE RESISTANCE PROTEIN A (Escherichia coli)	4 / 8	PHE A 292 GLY A 58 VAL A 214 LEU A 246	None	1.13A	3bgdB-2f1mA: undetectable	3bgdB-2f1mA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2f1m	ACRIFLAVINE RESISTANCE PROTEIN A (Escherichia coli)	5 / 9	ALA A 159 THR A 158 ALA A 156 ALA A 163 ASP A 111	None	1.18A	4qvnK-2f1mA: undetectable 4qvnL-2f1mA: undetectable	4qvnK-2f1mA: 22.81 4qvnL-2f1mA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2f1m	ACRIFLAVINE RESISTANCE PROTEIN A (Escherichia coli)	5 / 9	ALA A 159 THR A 158 ALA A 156 ALA A 163 ASP A 111	None	1.19A	4qvnY-2f1mA: undetectable 4qvnZ-2f1mA: undetectable	4qvnY-2f1mA: 22.81 4qvnZ-2f1mA: 20.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2JN3_A_JN3A131_2","FATTY ACID-BINDING PROTEIN, LIVER","2f1m","ACRIFLAVINE RESISTANCE PROTEIN A","Escherichia coli",4,"LEU A 246;GLN A 207;ILE A 212;PHE A 280","None","0.78A","2jn3A-2f1mA:undetectable","2jn3A-2f1mA:19.70"],["3BGD_B_PM6B301_1","THIOPURINE S-METHYLTRANSFERASE","2f1m","ACRIFLAVINE RESISTANCE PROTEIN A","Escherichia coli",4,"PHE A 292;GLY A  58;VAL A 214;LEU A 246","None","1.13A","3bgdB-2f1mA:undetectable","3bgdB-2f1mA:21.85"],["4QVN_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2f1m","ACRIFLAVINE RESISTANCE PROTEIN A","Escherichia coli",5,"ALA A 159;THR A 158;ALA A 156;ALA A 163;ASP A 111","None","1.18A","4qvnK-2f1mA:undetectable;4qvnL-2f1mA:undetectable","4qvnK-2f1mA:22.81;4qvnL-2f1mA:20.36"],["4QVN_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","2f1m","ACRIFLAVINE RESISTANCE PROTEIN A","Escherichia coli",5,"ALA A 159;THR A 158;ALA A 156;ALA A 163;ASP A 111","None","1.19A","4qvnY-2f1mA:undetectable;4qvnZ-2f1mA:undetectable","4qvnY-2f1mA:22.81;4qvnZ-2f1mA:20.36"]]