SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 2f1r MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN
B (MOBB)
(Archaeoglobus
fulgidus) 		5 / 9 GLU A 148
ASP A 147
ARG A 151
ILE A 152
ILE A 112
 None
 1.36A 1aj6A-2f1rA:
undetectable		 1aj6A-2f1rA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 2f1r MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN
B (MOBB)
(Archaeoglobus
fulgidus) 		4 / 5 GLU A 154
LEU A 160
LEU A 157
LEU A 159
 None
 0.97A 1np1A-2f1rA:
undetectable		 1np1A-2f1rA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2f1r MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN
B (MOBB)
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  34
VAL A  33
ILE A 156
LEU A  26
ILE A   7
 None
 0.99A 5nunA-2f1rA:
undetectable		 5nunA-2f1rA:
18.71