SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2f20 CONSERVED
HYPOTHETICAL
PROTEIN, WITH
CONSERVED DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  19
ILE A 132
ILE A  12
PRO A  47
ILE A  49
 None
 1.03A 1sduB-2f20A:
undetectable		 1sduB-2f20A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 2f20 CONSERVED
HYPOTHETICAL
PROTEIN, WITH
CONSERVED DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  19
ILE A 132
ILE A  12
PRO A  47
ILE A  49
 None
 0.94A 3nu3A-2f20A:
undetectable		 3nu3A-2f20A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2f20 CONSERVED
HYPOTHETICAL
PROTEIN, WITH
CONSERVED DOMAIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 102
TRP A 187
ILE A 197
 None
 0.81A 4mwxA-2f20A:
undetectable		 4mwxA-2f20A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 2f20 CONSERVED
HYPOTHETICAL
PROTEIN, WITH
CONSERVED DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  19
ILE A 132
ILE A  12
PRO A  47
ILE A  49
 None
 1.01A 6dh3B-2f20A:
undetectable		 6dh3B-2f20A:
15.86