SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.86A 1hshA-2f31A:
undetectable		 1hshA-2f31A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 9 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.82A 1hshB-2f31A:
undetectable		 1hshB-2f31A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 8 ALA A 238
GLY A 231
ILE A 232
ILE A 209
 None
 0.67A 1hshD-2f31A:
undetectable		 1hshD-2f31A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.05A 1v54A-2f31A:
undetectable
1v54J-2f31A:
undetectable		 1v54A-2f31A:
17.22
1v54J-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.86A 2b60B-2f31A:
undetectable		 2b60B-2f31A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 8 ILE A 208
ARG A 160
ARG A 210
ILE A 209
 None
 0.84A 2bu8A-2f31A:
undetectable		 2bu8A-2f31A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.05A 2dyrA-2f31A:
undetectable
2dyrJ-2f31A:
undetectable		 2dyrA-2f31A:
17.22
2dyrJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.05A 2dysA-2f31A:
undetectable
2dysJ-2f31A:
undetectable		 2dysA-2f31A:
17.22
2dysJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.05A 2dysN-2f31A:
undetectable
2dysW-2f31A:
undetectable		 2dysN-2f31A:
17.22
2dysW-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.07A 2eijA-2f31A:
0.9
2eijJ-2f31A:
undetectable		 2eijA-2f31A:
17.22
2eijJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.84A 2hs1A-2f31A:
undetectable		 2hs1A-2f31A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		3 / 3 THR A 297
ASP A 240
SER A 202
 None
 0.74A 2nxeA-2f31A:
undetectable		 2nxeA-2f31A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		3 / 3 THR A 297
ASP A 240
SER A 202
 None
 0.74A 2nxeB-2f31A:
undetectable		 2nxeB-2f31A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
 None
 1.12A 2q72A-2f31A:
undetectable		 2q72A-2f31A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
 None
 1.11A 2qb4A-2f31A:
undetectable		 2qb4A-2f31A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
 None
 1.13A 2qeiA-2f31A:
undetectable		 2qeiA-2f31A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU A 147
ARG A 148
ILE A 185
LEU A 189
ASP A 201
 None
 1.12A 2qjuA-2f31A:
undetectable		 2qjuA-2f31A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.79A 2rkfA-2f31A:
undetectable		 2rkfA-2f31A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.88A 2rkfB-2f31A:
undetectable		 2rkfB-2f31A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.83A 2rkgA-2f31A:
undetectable		 2rkgA-2f31A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.87A 2rkgB-2f31A:
undetectable		 2rkgB-2f31A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 ARG A 269
LEU B   9
ILE A 222
MET A 274
LEU A 254
 None
 1.14A 2v0mD-2f31A:
undetectable		 2v0mD-2f31A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.04A 3abmA-2f31A:
undetectable
3abmJ-2f31A:
undetectable		 3abmA-2f31A:
17.22
3abmJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.05A 3asnA-2f31A:
undetectable
3asnJ-2f31A:
undetectable		 3asnA-2f31A:
17.22
3asnJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 LEU A 234
MET A 225
THR A 224
LEU A 179
 None
 1.04A 3asoA-2f31A:
undetectable
3asoJ-2f31A:
undetectable		 3asoA-2f31A:
17.22
3asoJ-2f31A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ALA A 251
ILE A 248
THR A 297
SER A 298
LEU A 341
 None
 0.98A 3cl9A-2f31A:
undetectable		 3cl9A-2f31A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.96A 3ebzA-2f31A:
undetectable		 3ebzA-2f31A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 9 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.94A 3s45A-2f31A:
undetectable		 3s45A-2f31A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 ALA A 238
ILE A 208
GLY A 231
ILE A 232
ILE A 209
 None
 0.95A 3s53B-2f31A:
undetectable		 3s53B-2f31A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus;
Mus
musculus) 		5 / 11 MET B   6
GLY B   4
ASP B   7
ASN A 218
LEU A 253
 None
 1.17A 3v8vB-2f31B:
undetectable		 3v8vB-2f31B:
3.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 GLU A 318
ARG A 322
ASP A 320
ASP A 363
 None
 1.25A 4kcnB-2f31A:
undetectable		 4kcnB-2f31A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU A 156
ARG A 210
LEU A 186
LEU A 153
LEU A 182
 None
 1.30A 4or0A-2f31A:
2.4		 4or0A-2f31A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 LEU A 156
ARG A 210
LEU A 186
LEU A 153
LEU A 182
 None
 1.33A 4or0B-2f31A:
1.7		 4or0B-2f31A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 10 ALA A 278
VAL A 236
LEU A 308
LEU A 289
PHE A 286
 None
 1.30A 4zmeB-2f31A:
undetectable		 4zmeB-2f31A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 LEU A 179
LEU A 182
LEU A 186
MET B   6
LEU A 163
 None
 1.04A 4zn7A-2f31A:
undetectable		 4zn7A-2f31A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASN A 217
LEU A 260
PHE A 220
 None
 0.82A 5dsgA-2f31A:
undetectable		 5dsgA-2f31A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 GLY A 292
GLN A 336
LEU A 338
GLU A 340
LEU A 341
 None
 1.07A 5nwwA-2f31A:
undetectable		 5nwwA-2f31A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2f31 DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 7 ILE A 232
LEU A 235
ARG A 285
LEU A 308
 None
 0.95A 6nmpA-2f31A:
undetectable
6nmpJ-2f31A:
undetectable		 6nmpA-2f31A:
17.22
6nmpJ-2f31A:
12.45