SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.82A 1tyrB-2f3jA:
undetectable		 1tyrB-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 8 PHE A  98
PHE A 122
LEU A 149
SER A  80
 None
 1.00A 1wrlC-2f3jA:
undetectable
1wrlD-2f3jA:
undetectable		 1wrlC-2f3jA:
18.24
1wrlD-2f3jA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		5 / 12 ALA A 151
VAL A 106
LEU A  78
GLN A  92
LEU A 101
 None
 1.22A 2rctA-2f3jA:
undetectable		 2rctA-2f3jA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 6 GLN A 134
PHE A  98
PHE A  95
LEU A  77
 None
 1.13A 3ablP-2f3jA:
undetectable
3ablW-2f3jA:
undetectable		 3ablP-2f3jA:
21.85
3ablW-2f3jA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.89A 4d7bA-2f3jA:
undetectable		 4d7bA-2f3jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 8 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.83A 4iizB-2f3jA:
undetectable		 4iizB-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 8 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.81A 4ik7B-2f3jA:
undetectable		 4ik7B-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		5 / 12 PHE A  98
GLN A 148
LEU A  78
VAL A 120
LEU A  94
 None
 1.33A 4k39A-2f3jA:
undetectable		 4k39A-2f3jA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 6 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.86A 4pwjA-2f3jA:
undetectable		 4pwjA-2f3jA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.81A 4pwjB-2f3jA:
undetectable		 4pwjB-2f3jA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 6 GLN A 134
PHE A  98
PHE A  95
LEU A  77
 None
 1.11A 5b1bC-2f3jA:
undetectable
5b1bJ-2f3jA:
undetectable		 5b1bC-2f3jA:
21.85
5b1bJ-2f3jA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.83A 5bojB-2f3jA:
undetectable		 5bojB-2f3jA:
21.67