SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2f3n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3 (Rattus norvegicus)	4 / 7	LEU A 19 ARG A 25 ILE A 31 PHE A 26	None	1.01A	3ln1C-2f3nA: undetectable	3ln1C-2f3nA: 8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2f3n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3 (Rattus norvegicus)	4 / 5	LEU A 19 ARG A 25 ILE A 31 PHE A 26	None	1.01A	3ln1D-2f3nA: undetectable	3ln1D-2f3nA: 8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_C_HCYC1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2f3n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3 (Rattus norvegicus)	5 / 12	VAL A 49 ARG A 55 ILE A 58 PHE A 26 HIS A 35	None	1.41A	4c49C-2f3nA: undetectable	4c49C-2f3nA: 10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_D_HCYD1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2f3n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3 (Rattus norvegicus)	5 / 12	VAL A 49 ARG A 55 ILE A 58 PHE A 26 HIS A 35	None	1.34A	4c49D-2f3nA: undetectable	4c49D-2f3nA: 10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CE2_B_SVRB202_1 ()	2f3n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3 (Rattus norvegicus)	4 / 8	LEU A 65 LEU A 62 GLY A 11 LYS A 1	None	0.95A	6ce2A-2f3nA: undetectable	6ce2A-2f3nA: 21.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2f3n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3","Rattus norvegicus",4,"LEU A  19;ARG A  25;ILE A  31;PHE A  26","None","1.01A","3ln1C-2f3nA:undetectable","3ln1C-2f3nA:8.04"],["3LN1_D_CELD682_2","PROSTAGLANDIN G\/H SYNTHASE 2","2f3n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3","Rattus norvegicus",4,"LEU A  19;ARG A  25;ILE A  31;PHE A  26","None","1.01A","3ln1D-2f3nA:undetectable","3ln1D-2f3nA:8.04"],["4C49_C_HCYC1384_1","CORTICOSTEROID-BINDING GLOBULIN","2f3n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3","Rattus norvegicus",5,"VAL A  49;ARG A  55;ILE A  58;PHE A  26;HIS A  35","None","1.41A","4c49C-2f3nA:undetectable","4c49C-2f3nA:10.91"],["4C49_D_HCYD1384_1","CORTICOSTEROID-BINDING GLOBULIN","2f3n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3","Rattus norvegicus",5,"VAL A  49;ARG A  55;ILE A  58;PHE A  26;HIS A  35","None","1.34A","4c49D-2f3nA:undetectable","4c49D-2f3nA:10.91"],["6CE2_B_SVRB202_1",";","2f3n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS 3","Rattus norvegicus",4,"LEU A  65;LEU A  62;GLY A  11;LYS A   1","None","0.95A","6ce2A-2f3nA:undetectable","6ce2A-2f3nA:21.05"]]