SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 TYR A 149
GLU A 157
ASP A 164
 None
 0.61A 3bxoA-2f42A:
undetectable		 3bxoA-2f42A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 TYR A 149
GLU A 157
ASP A 164
 None
 0.58A 3bxoB-2f42A:
undetectable		 3bxoB-2f42A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 GLU A 239
LEU A 261
LEU A 265
 None
 0.77A 3ohtA-2f42A:
undetectable		 3ohtA-2f42A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 GLU A 239
LEU A 261
LEU A 265
 None
 0.75A 3ohtB-2f42A:
3.5		 3ohtB-2f42A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 ILE A 262
PRO A 263
ILE A 226
 None
 0.43A 5hw8F-2f42A:
undetectable		 5hw8F-2f42A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		4 / 8 GLN A 243
GLY A 246
ILE A 238
ASP A 249
 None
 1.03A 5vlmH-2f42A:
undetectable		 5vlmH-2f42A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2f42 STIP1 HOMOLOGY AND
U-BOX CONTAINING
PROTEIN 1
(Danio
rerio) 		3 / 3 LEU A 195
SER A 197
PHE A 196
 None
 0.67A 6fgcA-2f42A:
undetectable		 6fgcA-2f42A:
17.83