SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.14A 1akdA-2f43A:
undetectable		 1akdA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 ALA A 240
MET A 281
TYR A 278
LEU A 285
ARG A 304
 None
 1.31A 1iiuA-2f43A:
undetectable		 1iiuA-2f43A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.92A 1iwiA-2f43A:
undetectable		 1iwiA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.16A 1iwjA-2f43A:
0.0		 1iwjA-2f43A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 MET A 281
TYR A 278
LEU A 285
ARG A 304
TYR A 248
 None
 1.16A 1kt5A-2f43A:
undetectable		 1kt5A-2f43A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 10 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.16A 1o76A-2f43A:
undetectable		 1o76A-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.90A 1t85A-2f43A:
undetectable		 1t85A-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.22A 1t86B-2f43A:
undetectable		 1t86B-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.89A 1t87A-2f43A:
undetectable		 1t87A-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 ILE A 183
THR A 182
LEU A 265
VAL A 231
GLN A 208
 None
None
None
None
MG  A 602 (-4.2A)
 1.13A 1tw4A-2f43A:
undetectable		 1tw4A-2f43A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.92A 1yrcA-2f43A:
undetectable		 1yrcA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.93A 1yrdA-2f43A:
undetectable		 1yrdA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.11A 2a1nA-2f43A:
undetectable		 2a1nA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.14A 2a1nB-2f43A:
0.0		 2a1nB-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 10 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.17A 2cp4A-2f43A:
undetectable		 2cp4A-2f43A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.90A 2feuB-2f43A:
undetectable		 2feuB-2f43A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 VAL A  53
VAL A  74
ASP A  69
 None
 0.72A 2fumD-2f43A:
undetectable		 2fumD-2f43A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 ALA A 225
ASP A 224
GLY A 105
ILE A 230
 None
 0.83A 2fxdB-2f43A:
undetectable		 2fxdB-2f43A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 ASP A 347
VAL A 374
ALA A 377
THR A 322
 None
 0.95A 2q6oA-2f43A:
undetectable		 2q6oA-2f43A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 8 THR A 176
VAL A 213
THR A 212
ASP A 270
ILE A 206
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
None
 1.16A 2qbmA-2f43A:
undetectable		 2qbmA-2f43A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.92A 2zwtA-2f43A:
undetectable		 2zwtA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.93A 2zwuA-2f43A:
undetectable		 2zwuA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.16A 3cppA-2f43A:
0.0		 3cppA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 4 GLU A 353
GLY A 169
THR A 329
GLU A 328
 None
 1.18A 3e9xA-2f43A:
undetectable		 3e9xA-2f43A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 GLY A 250
VAL A 204
VAL A  97
VAL A 129
 None
 0.81A 3fi0B-2f43A:
undetectable		 3fi0B-2f43A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 GLY A 250
VAL A 204
VAL A  97
VAL A 129
 None
 0.76A 3fi0G-2f43A:
undetectable		 3fi0G-2f43A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 GLY A 250
VAL A 204
VAL A  97
VAL A 129
 None
 0.80A 3fi0I-2f43A:
undetectable		 3fi0I-2f43A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 GLY A 250
VAL A 204
VAL A  97
VAL A 129
 None
 0.75A 3fi0Q-2f43A:
undetectable		 3fi0Q-2f43A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.91A 3fwfA-2f43A:
undetectable		 3fwfA-2f43A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.90A 3fwfB-2f43A:
undetectable		 3fwfB-2f43A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.93A 3fwjA-2f43A:
undetectable		 3fwjA-2f43A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 SER A 233
ASP A 238
ASP A 269
 None
None
MG  A 602 (-3.7A)
 0.93A 3iv6C-2f43A:
undetectable		 3iv6C-2f43A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.91A 3l63A-2f43A:
undetectable		 3l63A-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 10 ILE A 115
MET A  62
PHE A  76
ALA A 240
LEU A 242
 None
 1.35A 3lw5B-2f43A:
undetectable		 3lw5B-2f43A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.90A 3wrhA-2f43A:
undetectable		 3wrhA-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.90A 3wrjA-2f43A:
undetectable		 3wrjA-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.91A 3wrlA-2f43A:
undetectable		 3wrlA-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.95A 3wrlE-2f43A:
undetectable		 3wrlE-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.93A 3wrmA-2f43A:
undetectable		 3wrmA-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.91A 3wrmF-2f43A:
undetectable		 3wrmF-2f43A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ASP A 154
LEU A 352
GLY A 149
ASN A 185
VAL A 153
 None
 1.00A 4dc3A-2f43A:
2.3		 4dc3A-2f43A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ASP A 154
LEU A 352
GLY A 149
ASN A 185
VAL A 153
 None
 0.92A 4dc3B-2f43A:
2.1		 4dc3B-2f43A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 9 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.20A 4ek1B-2f43A:
0.0		 4ek1B-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 LEU A 199
THR A 322
ILE A 159
VAL A 153
 None
 0.88A 4eq4B-2f43A:
undetectable		 4eq4B-2f43A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 ILE A 267
LEU A 265
ILE A 150
GLY A 160
 None
 0.90A 4hb6A-2f43A:
undetectable		 4hb6A-2f43A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 ILE A 267
LEU A 265
ILE A 150
GLY A 160
 None
 0.81A 4hb8A-2f43A:
undetectable		 4hb8A-2f43A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 PRO A 295
VAL A 298
PRO A 339
GLN A 274
 None
 1.05A 4iilA-2f43A:
2.7		 4iilA-2f43A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 8 THR A 176
THR A 235
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
None
MG  A 602 ( 4.8A)
 1.17A 4l4aA-2f43A:
undetectable		 4l4aA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 THR A 176
THR A 235
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 1.05A 4l4dA-2f43A:
undetectable		 4l4dA-2f43A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 THR A 176
THR A 235
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 1.11A 4l4eA-2f43A:
undetectable		 4l4eA-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 THR A 176
THR A 235
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 1.11A 4l4fA-2f43A:
undetectable		 4l4fA-2f43A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.88A 4l4gA-2f43A:
undetectable		 4l4gA-2f43A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA304_1
(CHITOSANASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 4 TYR A 228
ILE A 183
THR A 229
TYR A 433
 None
 1.09A 4oltA-2f43A:
0.0		 4oltA-2f43A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 TYR A 228
ILE A 183
THR A 229
TYR A 433
 None
 1.07A 4oltB-2f43A:
0.0		 4oltB-2f43A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 8 PHE A 299
THR A 346
SER A 344
TYR A 268
 None
 1.10A 4qb9D-2f43A:
undetectable		 4qb9D-2f43A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 TYR A 228
ILE A 183
THR A 229
TYR A 433
 None
 1.10A 4qwpA-2f43A:
undetectable		 4qwpA-2f43A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 TYR A 228
ILE A 183
THR A 229
TYR A 433
 None
 1.03A 4qwpB-2f43A:
0.0		 4qwpB-2f43A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 VAL A  31
ILE A  34
VAL A  73
ALA A  39
 None
 0.76A 5ospA-2f43A:
undetectable		 5ospA-2f43A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 12 ILE A 115
MET A  62
PHE A  76
ALA A 240
LEU A 242
 None
 1.29A 5oy02-2f43A:
undetectable		 5oy02-2f43A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 7 THR A 176
LEU A 216
VAL A 213
ASP A 270
 MG  A 602 ( 3.3A)
None
None
MG  A 602 ( 4.8A)
 0.86A 5wk9A-2f43A:
undetectable		 5wk9A-2f43A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 10 GLY A  58
VAL A  53
VAL A  41
VAL A  75
ALA A  39
 None
 1.04A 6czmA-2f43A:
undetectable
6czmC-2f43A:
undetectable		 6czmA-2f43A:
23.18
6czmC-2f43A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 6 ALA A 402
GLY A 421
THR A 425
ILE A 361
 None
 0.80A 6f8cA-2f43A:
undetectable		 6f8cA-2f43A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2f43 ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 7 VAL A  99
ILE A 202
GLY A 207
ARG A 128
ALA A 246
 None
 1.44A 6hd6B-2f43A:
undetectable		 6hd6B-2f43A:
9.53