SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f4p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 6 TRP A  22
GLY A  46
ASN A  20
PRO A  99
 None
 1.19A 1dedA-2f4pA:
2.1		 1dedA-2f4pA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 1v54A-2f4pA:
undetectable		 1v54A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.76A 1v54N-2f4pA:
undetectable		 1v54N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 1v55A-2f4pA:
undetectable		 1v55A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 1v55N-2f4pA:
undetectable		 1v55N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 6 ALA A  47
HIS A 105
ASP A  40
TYR A  39
 None
None
None
UNL  A 136 (-3.5A)
 1.26A 2dpzA-2f4pA:
undetectable		 2dpzA-2f4pA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.73A 2dyrA-2f4pA:
undetectable		 2dyrA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.76A 2dyrN-2f4pA:
undetectable		 2dyrN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 2eijA-2f4pA:
undetectable		 2eijA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 2eijN-2f4pA:
undetectable		 2eijN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 2eikA-2f4pA:
undetectable		 2eikA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.75A 2eikN-2f4pA:
undetectable		 2eikN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.75A 2eilA-2f4pA:
undetectable		 2eilA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 2eimA-2f4pA:
undetectable		 2eimA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 2eimN-2f4pA:
undetectable		 2eimN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 LEU A  60
LEU A  26
MET A  25
 None
 0.79A 2itzA-2f4pA:
undetectable		 2itzA-2f4pA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.77A 2y69N-2f4pA:
undetectable		 2y69N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		5 / 12 VAL A  23
SER A  10
SER A  13
HIS A  95
LEU A  60
 UNL  A 136 ( 4.9A)
None
None
UNL  A 136 (-3.9A)
None
 1.43A 2zlcA-2f4pA:
undetectable		 2zlcA-2f4pA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3abkA-2f4pA:
undetectable		 3abkA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3abkN-2f4pA:
undetectable		 3abkN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.76A 3abmA-2f4pA:
undetectable		 3abmA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.68A 3ag1A-2f4pA:
undetectable		 3ag1A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.68A 3ag1N-2f4pA:
undetectable		 3ag1N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 3ag2A-2f4pA:
undetectable		 3ag2A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.75A 3ag2N-2f4pA:
undetectable		 3ag2N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3ag3A-2f4pA:
undetectable		 3ag3A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3ag3N-2f4pA:
undetectable		 3ag3N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.57A 3ag4A-2f4pA:
undetectable		 3ag4A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.62A 3ag4N-2f4pA:
undetectable		 3ag4N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3asnA-2f4pA:
undetectable		 3asnA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3asoA-2f4pA:
undetectable		 3asoA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.75A 3dtuA-2f4pA:
undetectable		 3dtuA-2f4pA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 3dtuC-2f4pA:
undetectable		 3dtuC-2f4pA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 3x2qA-2f4pA:
undetectable		 3x2qA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		5 / 10 HIS A  93
HIS A  52
HIS A  95
HIS A 105
TYR A  39
 None
UNL  A 136 (-3.3A)
UNL  A 136 (-3.9A)
None
UNL  A 136 (-3.5A)
 1.47A 4bz6A-2f4pA:
undetectable		 4bz6A-2f4pA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		5 / 12 HIS A  93
HIS A  52
HIS A  95
HIS A 105
TYR A  39
 None
UNL  A 136 (-3.3A)
UNL  A 136 (-3.9A)
None
UNL  A 136 (-3.5A)
 1.47A 4bz6A-2f4pA:
undetectable
4bz6B-2f4pA:
undetectable		 4bz6A-2f4pA:
15.80
4bz6B-2f4pA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		5 / 10 HIS A  93
HIS A  52
HIS A  95
HIS A 105
TYR A  39
 None
UNL  A 136 (-3.3A)
UNL  A 136 (-3.9A)
None
UNL  A 136 (-3.5A)
 1.47A 4bz6D-2f4pA:
undetectable		 4bz6D-2f4pA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 5 HIS A  52
ALA A 117
HIS A  54
GLN A  58
 UNL  A 136 (-3.3A)
UNL  A 136 ( 4.9A)
UNL  A 136 (-3.7A)
UNL  A 136 (-3.2A)
 0.99A 4gboA-2f4pA:
undetectable		 4gboA-2f4pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 5 HIS A  52
ALA A 117
HIS A  54
GLN A  58
 UNL  A 136 (-3.3A)
UNL  A 136 ( 4.9A)
UNL  A 136 (-3.7A)
UNL  A 136 (-3.2A)
 1.12A 4gboB-2f4pA:
undetectable		 4gboB-2f4pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.70A 5b1bA-2f4pA:
undetectable		 5b1bA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 5b1bN-2f4pA:
undetectable		 5b1bN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 5b3sA-2f4pA:
undetectable		 5b3sA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.75A 5b3sN-2f4pA:
undetectable		 5b3sN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 5iy5A-2f4pA:
undetectable		 5iy5A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 5iy5N-2f4pA:
undetectable		 5iy5N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 8 HIS A  52
HIS A  54
GLY A  57
SER A 109
 UNL  A 136 (-3.3A)
UNL  A 136 (-3.7A)
None
UNL  A 136 ( 4.7A)
 0.87A 5m8rC-2f4pA:
undetectable		 5m8rC-2f4pA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		4 / 5 HIS A  52
ALA A 117
HIS A  54
GLN A  58
 UNL  A 136 (-3.3A)
UNL  A 136 ( 4.9A)
UNL  A 136 (-3.7A)
UNL  A 136 (-3.2A)
 0.97A 5uizA-2f4pA:
undetectable		 5uizA-2f4pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.73A 5w97a-2f4pA:
undetectable		 5w97a-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.74A 5waua-2f4pA:
undetectable		 5waua-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.70A 5x19A-2f4pA:
undetectable		 5x19A-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.71A 5x19N-2f4pA:
undetectable		 5x19N-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.70A 5x1fA-2f4pA:
undetectable		 5x1fA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.69A 5x1fN-2f4pA:
undetectable		 5x1fN-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.76A 6giqa-2f4pA:
undetectable		 6giqa-2f4pA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.72A 6nmfA-2f4pA:
undetectable		 6nmfA-2f4pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f4p HYPOTHETICAL PROTEIN
TM1010
(Thermotoga
maritima) 		3 / 3 HIS A  95
HIS A  52
HIS A  93
 UNL  A 136 (-3.9A)
UNL  A 136 (-3.3A)
None
 0.70A 6nmfN-2f4pA:
undetectable		 6nmfN-2f4pA:
14.12