SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		5 / 11 LEU A  93
ILE A  78
ARG A  86
TYR A  56
GLY A 117
 None
 1.31A 2bxeA-2f4wA:
undetectable		 2bxeA-2f4wA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		4 / 7 SER A 146
TYR A  61
VAL A  47
ILE A 167
 None
 1.24A 2x45B-2f4wA:
undetectable		 2x45B-2f4wA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		4 / 7 SER A 146
TYR A  61
VAL A  47
ILE A 167
 None
 1.24A 2x45C-2f4wA:
undetectable		 2x45C-2f4wA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		3 / 3 ILE A  32
VAL A  48
PRO A  51
 None
 0.68A 5uunA-2f4wA:
undetectable		 5uunA-2f4wA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		3 / 3 LEU A 142
GLN A 145
LYS A  88
 None
 0.86A 6exiB-2f4wA:
undetectable		 6exiB-2f4wA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2f4w UBIQUITIN-CONJUGATIN
G ENZYME E2, J2
(Homo
sapiens) 		3 / 3 LEU A 142
GLN A 145
LYS A  88
 None
 0.88A 6exiA-2f4wA:
undetectable		 6exiA-2f4wA:
17.02