SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2f51 THIOREDOXIN
(Trichomonas
vaginalis) 		4 / 7 LEU A  80
PHE A  82
ILE A  48
GLY A  98
 None
 1.02A 2v0mC-2f51A:
undetectable		 2v0mC-2f51A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 2f51 THIOREDOXIN
(Trichomonas
vaginalis) 		5 / 12 ILE A  48
PHE A  81
ILE A  19
VAL A  26
VAL A  55
 None
 1.18A 3iw1A-2f51A:
undetectable		 3iw1A-2f51A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 2f51 THIOREDOXIN
(Trichomonas
vaginalis) 		5 / 12 LEU A  80
ILE A 104
ILE A 108
PHE A  57
LEU A  45
 None
 1.03A 5uanB-2f51A:
undetectable		 5uanB-2f51A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2f51 THIOREDOXIN
(Trichomonas
vaginalis) 		4 / 7 ALA A  68
THR A  11
ILE A  58
VAL A  60
 None
 0.86A 6cduF-2f51A:
undetectable
6cduJ-2f51A:
undetectable		 6cduF-2f51A:
16.00
6cduJ-2f51A:
16.00