SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f5g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		3 / 3 THR A  36
LEU A  40
LEU A  47
 None
 0.65A 1mz9C-2f5gA:
undetectable		 1mz9C-2f5gA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2003_0
(TRYPTOPHAN
HALOGENASE)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		5 / 12 PRO A  68
GLU A  45
TYR A  75
TYR A  71
PHE A  80
 None
 1.40A 2oa1B-2f5gA:
3.6		 2oa1B-2f5gA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		4 / 8 TYR A  79
GLU A  46
TYR A  71
LEU A  76
 None
 1.12A 3rqwC-2f5gA:
undetectable
3rqwD-2f5gA:
undetectable		 3rqwC-2f5gA:
15.53
3rqwD-2f5gA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		4 / 8 GLU A  46
TYR A  71
LEU A  76
TYR A  79
 None
 1.12A 3rqwF-2f5gA:
undetectable
3rqwJ-2f5gA:
undetectable		 3rqwF-2f5gA:
15.53
3rqwJ-2f5gA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		5 / 10 ALA A  72
LEU A  76
VAL A  65
ILE A  43
ALA A  44
 None
 1.04A 4j14A-2f5gA:
undetectable		 4j14A-2f5gA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 2f5g TRANSPOSASE,
PUTATIVE
(Sulfolobus
solfataricus) 		3 / 3 LEU A  40
LYS A  37
THR A  36
 None
 0.60A 4lj0A-2f5gA:
undetectable		 4lj0A-2f5gA:
19.23