SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		3 / 3 THR A 188
THR A 186
PRO A 191
 None
 0.85A 1a7yA-2f5uA:
undetectable		 1a7yA-2f5uA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 5 ARG A 227
ALA A 300
ASP A 371
GLY A 304
 None
 1.15A 1e7cA-2f5uA:
undetectable		 1e7cA-2f5uA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		3 / 3 THR A 186
PRO A 191
THR A 188
 None
 0.87A 1i3wE-2f5uA:
undetectable		 1i3wE-2f5uA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 5 TYR A 289
GLU A 532
TYR A 306
PRO A 295
 None
 1.33A 1mclA-2f5uA:
0.0
1mclB-2f5uA:
0.0
1mclP-2f5uA:
undetectable		 1mclA-2f5uA:
17.90
1mclB-2f5uA:
17.90
1mclP-2f5uA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		3 / 3 THR A 186
PRO A 191
THR A 188
 None
 0.83A 1ovfB-2f5uA:
undetectable		 1ovfB-2f5uA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 LEU A 443
TYR A 447
ILE A 140
GLY A 466
 None
 0.67A 2du8A-2f5uA:
undetectable		 2du8A-2f5uA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 LEU A 443
TYR A 447
ILE A 140
GLY A 466
 None
 0.70A 2du8B-2f5uA:
undetectable		 2du8B-2f5uA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 9 LEU A 375
LEU A 368
ILE A 352
LEU A 320
ILE A 317
 None
 1.16A 2f78A-2f5uA:
undetectable		 2f78A-2f5uA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 9 LEU A 375
LEU A 368
ILE A 352
LEU A 320
ILE A 317
 None
 1.12A 2f78B-2f5uA:
undetectable		 2f78B-2f5uA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 10 LEU A 375
LEU A 368
ILE A 352
LEU A 320
ILE A 317
 None
 1.11A 2f8dA-2f5uA:
undetectable		 2f8dA-2f5uA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 10 LEU A 375
LEU A 368
ILE A 352
LEU A 320
ILE A 317
 None
 1.11A 2f8dB-2f5uA:
undetectable		 2f8dB-2f5uA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 LEU A 565
MET A 564
SER A 435
GLY A 466
LEU A 460
 None
 1.14A 2lbdA-2f5uA:
undetectable		 2lbdA-2f5uA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 11 LEU A 470
PHE A 553
LEU A 568
MET A 564
LEU A 440
 None
 1.34A 2po5B-2f5uA:
undetectable		 2po5B-2f5uA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PHE A 299
LEU A 538
LEU A 535
ALA A 469
GLU A 459
 None
 1.26A 2v0mC-2f5uA:
undetectable		 2v0mC-2f5uA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.27A 2zd1A-2f5uA:
undetectable		 2zd1A-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 8 ARG A 390
ALA A 275
ILE A 278
PRO A 285
 None
 0.89A 3fxrA-2f5uA:
undetectable		 3fxrA-2f5uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 THR A 510
THR A 502
ALA A 211
ALA A 197
SER A 205
 None
 1.06A 3mg02-2f5uA:
undetectable
3mg0V-2f5uA:
undetectable		 3mg02-2f5uA:
20.05
3mg0V-2f5uA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		3 / 3 GLY A 386
ILE A 315
VAL A 316
 None
 0.40A 3nv6A-2f5uA:
undetectable		 3nv6A-2f5uA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 LEU A 222
ALA A 377
THR A 378
ASN A 380
LEU A 237
 None
 1.19A 3r9cA-2f5uA:
undetectable		 3r9cA-2f5uA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 11 LEU A 408
LEU A 411
ILE A 412
LEU A 147
ILE A 573
 None
 1.14A 4dm8A-2f5uA:
undetectable		 4dm8A-2f5uA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 11 LEU A 408
LEU A 411
ILE A 412
SER A 171
ILE A 573
 None
 1.18A 4dm8A-2f5uA:
undetectable		 4dm8A-2f5uA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.28A 4iclA-2f5uA:
0.0		 4iclA-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.31A 4id5A-2f5uA:
undetectable		 4id5A-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.30A 4idkA-2f5uA:
0.0		 4idkA-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.32A 4ifvA-2f5uA:
undetectable		 4ifvA-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.33A 4ifyA-2f5uA:
undetectable		 4ifyA-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.30A 4ig3A-2f5uA:
0.2		 4ig3A-2f5uA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		3 / 3 PRO A 327
LEU A 326
GLN A 372
 None
 0.65A 4pevB-2f5uA:
undetectable		 4pevB-2f5uA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 SER A 205
THR A 510
THR A 502
ALA A 211
ALA A 197
 None
 1.08A 4qvnV-2f5uA:
undetectable
4qvnb-2f5uA:
undetectable		 4qvnV-2f5uA:
19.25
4qvnb-2f5uA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 SER A 205
THR A 510
THR A 502
ALA A 211
ALA A 197
 None
 1.08A 4qvnH-2f5uA:
undetectable
4qvnN-2f5uA:
undetectable		 4qvnH-2f5uA:
19.25
4qvnN-2f5uA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 LEU A 546
LEU A 470
ILE A 573
PHE A 567
 None
 0.85A 4y4dA-2f5uA:
undetectable		 4y4dA-2f5uA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 PHE A 464
LEU A 153
ASN A 152
PRO A 154
 None
 1.39A 4yv5B-2f5uA:
0.7		 4yv5B-2f5uA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 PHE A 464
LEU A 153
ASN A 152
PRO A 154
 None
 1.40A 4yv5A-2f5uA:
0.6		 4yv5A-2f5uA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 5 TYR A 562
LEU A 147
PRO A 145
LEU A 411
 None
 1.47A 5eshA-2f5uA:
0.0		 5eshA-2f5uA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 5 ALA A 528
TYR A 531
GLY A 261
LEU A 385
 None
 0.78A 5eslA-2f5uA:
undetectable		 5eslA-2f5uA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 4 GLN A 183
THR A 186
LEU A 216
LEU A 212
 None
 1.21A 5m5kB-2f5uA:
undetectable		 5m5kB-2f5uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 7 LEU A 460
LEU A 449
ILE A 388
GLY A 386
LEU A 271
 None
 1.11A 5vkqA-2f5uA:
undetectable
5vkqB-2f5uA:
undetectable		 5vkqA-2f5uA:
13.49
5vkqB-2f5uA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 8 LEU A 460
LEU A 449
ILE A 388
GLY A 386
LEU A 271
 None
 1.12A 5vkqB-2f5uA:
undetectable
5vkqC-2f5uA:
undetectable		 5vkqB-2f5uA:
13.49
5vkqC-2f5uA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 TYR A 287
ILE A 382
LEU A 274
GLY A 536
ALA A 539
 None
 1.14A 5zwrA-2f5uA:
undetectable		 5zwrA-2f5uA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 PRO A 574
LEU A 406
VAL A 416
PRO A 145
TYR A 562
 None
 1.36A 6eliA-2f5uA:
undetectable		 6eliA-2f5uA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 VAL A 236
LEU A 267
ALA A 235
THR A 378
LEU A 264
 None
 1.04A 6f6iA-2f5uA:
undetectable
6f6iB-2f5uA:
undetectable		 6f6iA-2f5uA:
12.06
6f6iB-2f5uA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 5 ARG A 494
ALA A 493
GLN A 495
ILE A 182
 None
 0.99A 6f6sA-2f5uA:
undetectable
6f6sB-2f5uA:
undetectable		 6f6sA-2f5uA:
12.06
6f6sB-2f5uA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		4 / 6 MET A 564
GLY A 571
ALA A 468
LEU A 467
 None
 0.99A 6fosA-2f5uA:
undetectable		 6fosA-2f5uA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 SER A 205
THR A 510
THR A 502
ALA A 211
ALA A 197
 None
 1.09A 6hwdV-2f5uA:
undetectable
6hwdb-2f5uA:
undetectable		 6hwdV-2f5uA:
10.74
6hwdb-2f5uA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 2f5u VIRION PROTEIN UL25
(Human
alphaherpesvirus
1) 		5 / 12 SER A 205
THR A 510
THR A 502
ALA A 211
ALA A 197
 None
 1.09A 6hwdH-2f5uA:
undetectable
6hwdN-2f5uA:
undetectable		 6hwdH-2f5uA:
10.74
6hwdN-2f5uA:
10.27