SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 9 VAL A  52
GLY A  53
ASP A  76
ILE A  77
ALA A 320
 FAD  A1625 (-4.8A)
FAD  A1625 (-3.4A)
FAD  A1625 (-2.9A)
FAD  A1625 (-3.9A)
FAD  A1625 (-3.6A)
 0.59A 1cetA-2f5vA:
4.2		 1cetA-2f5vA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 8 GLY A 584
GLY A 582
HIS A 167
VAL A 157
 None
FAD  A1625 ( 3.9A)
FAD  A1625 (-2.8A)
None
 0.91A 1dbbH-2f5vA:
undetectable
1dbbL-2f5vA:
undetectable		 1dbbH-2f5vA:
15.62
1dbbL-2f5vA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 THR A 595
THR A 597
PRO A 594
 FAD  A1625 (-3.4A)
None
FAD  A1625 ( 4.4A)
 0.83A 1dscC-2f5vA:
undetectable		 1dscC-2f5vA:
2.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 CYH A 564
HIS A 553
SER A 570
LEU A 580
LEU A 578
 None
 1.42A 1hwkB-2f5vA:
2.8		 1hwkB-2f5vA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 CYH A 564
HIS A 553
SER A 570
LEU A 580
LEU A 578
 None
 1.43A 1hwkA-2f5vA:
3.3		 1hwkA-2f5vA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 CYH A 564
HIS A 553
SER A 570
LEU A 580
LEU A 578
 None
 1.44A 1hwkD-2f5vA:
0.0		 1hwkD-2f5vA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 CYH A 564
HIS A 553
SER A 570
LEU A 580
LEU A 578
 None
 1.44A 1hwkC-2f5vA:
0.0		 1hwkC-2f5vA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 1liiA-2f5vA:
2.4		 1liiA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.99A 1likA-2f5vA:
2.2		 1likA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 SER A 165
GLY A  87
VAL A 161
SER A 255
ILE A  86
 None
 1.20A 1pk9C-2f5vA:
undetectable		 1pk9C-2f5vA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 11 PHE A 487
LEU A 578
VAL A 572
PHE A 334
VAL A 286
 None
 1.41A 1q23J-2f5vA:
undetectable		 1q23J-2f5vA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 6 THR A 169
GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 ( 3.7A)
KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.32A 1tt0A-2f5vA:
63.8		 1tt0A-2f5vA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 6 THR A 169
GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 ( 3.7A)
KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.31A 1tt0B-2f5vA:
63.9		 1tt0B-2f5vA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 6 THR A 169
GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 ( 3.7A)
KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.34A 1tt0C-2f5vA:
22.8		 1tt0C-2f5vA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 6 THR A 169
GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 ( 3.7A)
KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.31A 1tt0D-2f5vA:
64.0		 1tt0D-2f5vA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 6 ASN A 585
HIS A 553
ILE A 603
THR A 319
 None
 1.26A 2hkkA-2f5vA:
undetectable		 2hkkA-2f5vA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 9 LEU A 329
ILE A  77
GLY A  53
ILE A  51
VAL A 286
 None
FAD  A1625 (-3.9A)
FAD  A1625 (-3.4A)
None
None
 1.17A 2r5qA-2f5vA:
undetectable		 2r5qA-2f5vA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 9 LEU A 329
ILE A  77
GLY A  53
ILE A  51
VAL A 286
 None
FAD  A1625 (-3.9A)
FAD  A1625 (-3.4A)
None
None
 1.17A 2r5qC-2f5vA:
undetectable		 2r5qC-2f5vA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 VAL A 160
GLY A 163
GLY A  55
SER A  82
THR A 158
 None
FAD  A1625 (-3.1A)
FAD  A1625 (-3.3A)
None
None
 1.38A 3dh0A-2f5vA:
undetectable		 3dh0A-2f5vA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		6 / 12 LEU A 329
GLY A 321
ALA A 320
ILE A  77
ILE A  51
VAL A 286
 None
FAD  A1625 ( 3.9A)
FAD  A1625 (-3.6A)
FAD  A1625 (-3.9A)
None
None
 1.49A 3jw2B-2f5vA:
undetectable		 3jw2B-2f5vA:
11.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 6 GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.15A 3lskB-2f5vA:
63.5		 3lskB-2f5vA:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 6 GLN A 448
PHE A 474
HIS A 548
ASN A 593
 KBG  A1628 (-3.0A)
KBG  A1628 (-4.7A)
KBG  A1628 (-3.6A)
KBG  A1628 ( 3.8A)
 0.17A 3lskD-2f5vA:
63.5		 3lskD-2f5vA:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 VAL A 286
VAL A 572
LEU A 578
GLY A 335
LEU A 329
 None
 1.13A 3pghA-2f5vA:
undetectable		 3pghA-2f5vA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 5 ILE A 586
THR A 597
THR A 595
PHE A 175
 None
None
FAD  A1625 (-3.4A)
None
 1.03A 3snfA-2f5vA:
undetectable		 3snfA-2f5vA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.95A 3uboA-2f5vA:
undetectable		 3uboA-2f5vA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.93A 3uboB-2f5vA:
2.8		 3uboB-2f5vA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 4 PRO A 423
LEU A 424
ILE A 426
ARG A 218
 None
 1.30A 3w1wA-2f5vA:
undetectable		 3w1wA-2f5vA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4e3aA-2f5vA:
2.8		 4e3aA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 6 GLN A 155
PHE A 502
PRO A 543
PHE A 504
 None
 1.18A 4fgkA-2f5vA:
undetectable		 4fgkA-2f5vA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 8 PRO A 433
ASN A 224
ILE A 449
MET A 368
 None
 1.07A 4iilA-2f5vA:
2.3		 4iilA-2f5vA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		6 / 12 GLY A  53
ASP A  76
ILE A  77
ALA A 320
HIS A 324
LEU A 328
 FAD  A1625 (-3.4A)
FAD  A1625 (-2.9A)
FAD  A1625 (-3.9A)
FAD  A1625 (-3.6A)
FAD  A1625 (-4.1A)
None
 1.12A 4iv8A-2f5vA:
undetectable		 4iv8A-2f5vA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		6 / 12 GLY A  53
ASP A  76
ILE A  77
ALA A 320
HIS A 324
LEU A 328
 FAD  A1625 (-3.4A)
FAD  A1625 (-2.9A)
FAD  A1625 (-3.9A)
FAD  A1625 (-3.6A)
FAD  A1625 (-4.1A)
None
 1.10A 4iv8B-2f5vA:
undetectable		 4iv8B-2f5vA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		6 / 12 LEU A 329
GLY A 321
ALA A 320
ILE A  77
ILE A  51
VAL A 286
 None
FAD  A1625 ( 3.9A)
FAD  A1625 (-3.6A)
FAD  A1625 (-3.9A)
None
None
 1.50A 4jecA-2f5vA:
undetectable		 4jecA-2f5vA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.99A 4jksA-2f5vA:
2.8		 4jksA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4jksB-2f5vA:
2.9		 4jksB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4jkuA-2f5vA:
3.2		 4jkuA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4jkuB-2f5vA:
2.8		 4jkuB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4k8cA-2f5vA:
3.2		 4k8cA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.99A 4k8cB-2f5vA:
2.8		 4k8cB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.99A 4k8kA-2f5vA:
2.8		 4k8kA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 1.00A 4k8kB-2f5vA:
2.8		 4k8kB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4k8pA-2f5vA:
2.8		 4k8pA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4k8pB-2f5vA:
2.8		 4k8pB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4k8tA-2f5vA:
2.9		 4k8tA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4k8tB-2f5vA:
2.8		 4k8tB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4k93A-2f5vA:
3.2		 4k93A-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4k93B-2f5vA:
2.9		 4k93B-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4k9cA-2f5vA:
2.8		 4k9cA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4k9cB-2f5vA:
2.8		 4k9cB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4k9iA-2f5vA:
2.8		 4k9iA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.95A 4k9iB-2f5vA:
2.8		 4k9iB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4kadA-2f5vA:
3.1		 4kadA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.95A 4kadB-2f5vA:
3.1		 4kadB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4kahA-2f5vA:
3.1		 4kahA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kahB-2f5vA:
2.8		 4kahB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kalA-2f5vA:
2.7		 4kalA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kalB-2f5vA:
2.8		 4kalB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kanA-2f5vA:
3.3		 4kanA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kanB-2f5vA:
2.8		 4kanB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kbeA-2f5vA:
3.2		 4kbeA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4kbeB-2f5vA:
3.2		 4kbeB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4lbgA-2f5vA:
2.9		 4lbgA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4lbgB-2f5vA:
2.9		 4lbgB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4lbxA-2f5vA:
2.8		 4lbxA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.96A 4lbxB-2f5vA:
2.8		 4lbxB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4lc4A-2f5vA:
2.9		 4lc4A-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4lc4B-2f5vA:
2.8		 4lc4B-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.97A 4lcaA-2f5vA:
2.8		 4lcaA-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A  57
GLY A 581
GLY A 582
ASN A 585
THR A  60
 FAD  A1625 (-4.0A)
None
FAD  A1625 ( 3.9A)
None
None
 0.98A 4lcaB-2f5vA:
2.8		 4lcaB-2f5vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 9 THR A 595
ALA A 598
LEU A 198
TYR A  61
THR A  60
 FAD  A1625 (-3.4A)
None
None
None
None
 1.38A 4ltwA-2f5vA:
undetectable		 4ltwA-2f5vA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 GLN A 440
HIS A 443
ARG A 234
 None
 1.01A 4qyqA-2f5vA:
undetectable		 4qyqA-2f5vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 GLN A 440
HIS A 443
ARG A 234
 None
 1.07A 4qyqB-2f5vA:
undetectable		 4qyqB-2f5vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		4 / 6 GLU A 273
GLY A  53
ASP A  76
GLY A  58
 None
FAD  A1625 (-3.4A)
FAD  A1625 (-2.9A)
None
 0.92A 5cdpA-2f5vA:
undetectable
5cdpB-2f5vA:
undetectable		 5cdpA-2f5vA:
20.47
5cdpB-2f5vA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 MET A 519
THR A 366
GLY A 530
ILE A 529
GLY A 535
 None
 1.00A 5d4uC-2f5vA:
undetectable		 5d4uC-2f5vA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 MET A 519
THR A 366
GLY A 530
ILE A 529
GLY A 535
 None
 1.02A 5d4uD-2f5vA:
1.6		 5d4uD-2f5vA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A 295
ALA A 320
VAL A  52
GLY A 584
THR A 552
 None
FAD  A1625 (-3.6A)
FAD  A1625 (-4.8A)
None
None
 1.22A 5igiA-2f5vA:
undetectable		 5igiA-2f5vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 ILE A 295
ALA A 320
VAL A  52
GLY A 584
THR A 552
 None
FAD  A1625 (-3.6A)
FAD  A1625 (-4.8A)
None
None
 1.21A 5igpA-2f5vA:
undetectable		 5igpA-2f5vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 9 LEU A 329
ASN A 325
ILE A  77
ILE A  51
VAL A 286
 None
None
FAD  A1625 (-3.9A)
None
None
 1.12A 5kr2D-2f5vA:
undetectable		 5kr2D-2f5vA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 ARG A 554
PHE A 579
LEU A 601
 None
 0.77A 5veuA-2f5vA:
undetectable		 5veuA-2f5vA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 HIS A 419
HIS A 415
ARG A 466
 None
 1.12A 6b58A-2f5vA:
15.9		 6b58A-2f5vA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		3 / 3 GLY A  55
ASP A  76
ILE A  80
 FAD  A1625 (-3.3A)
FAD  A1625 (-2.9A)
None
 0.57A 6dgxB-2f5vA:
undetectable		 6dgxB-2f5vA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 VAL A 323
ASP A  76
VAL A 161
SER A  82
VAL A 157
 None
FAD  A1625 (-2.9A)
None
None
None
 1.41A 6h7lA-2f5vA:
undetectable		 6h7lA-2f5vA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 2f5v PYRANOSE 2-OXIDASE
(Peniophora
sp.
SG) 		5 / 12 VAL A 323
ASP A  76
VAL A 161
SER A  82
VAL A 157
 None
FAD  A1625 (-2.9A)
None
None
None
 1.43A 6h7lB-2f5vA:
undetectable		 6h7lB-2f5vA:
10.24