SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 2f66 SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
PROTEIN SRN2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 ASP C 182
GLN A 362
GLN A 369
LYS C 186
 None
 1.20A 6g31A-2f66C:
5.6		 6g31A-2f66C:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 2f66 SUPPRESSOR PROTEIN
STP22 OF
TEMPERATURE-SENSITIV
E ALPHA-FACTOR
RECEPTOR AND
ARGININE PERMEASE
PROTEIN SRN2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 11 THR C 172
PHE C 184
THR A 341
ILE A 342
MET A 348
 None
 1.43A 6hcoA-2f66C:
2.5
6hcoB-2f66C:
undetectable		 6hcoA-2f66C:
7.77
6hcoB-2f66C:
7.77