SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 11 GLY A 270
TYR A 269
PRO A 266
PHE A 247
VAL A 263
 None
 1.20A 2fl5A-2f6aA:
3.5
2fl5B-2f6aA:
5.3
2fl5F-2f6aA:
5.3		 2fl5A-2f6aA:
23.10
2fl5B-2f6aA:
20.77
2fl5F-2f6aA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 5 ASN A 193
ASP A 179
GLU A  86
SER A 276
 None
 1.43A 3p2kC-2f6aA:
undetectable		 3p2kC-2f6aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 8 ILE A 207
ILE A 194
PHE A 275
VAL A 201
GLY A 270
 None
 1.30A 4ac9C-2f6aA:
undetectable		 4ac9C-2f6aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		3 / 3 ASP A  40
ASN A 155
SER A 126
 None
 0.84A 4obwA-2f6aA:
undetectable		 4obwA-2f6aA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 6 ASP A  50
ARG A 136
GLY A 135
GLU A  86
 None
 1.03A 5cdqA-2f6aA:
undetectable
5cdqC-2f6aA:
undetectable
5cdqD-2f6aA:
undetectable		 5cdqA-2f6aA:
19.80
5cdqC-2f6aA:
19.80
5cdqD-2f6aA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 12 PRO A  93
ALA A 104
THR A  55
ILE A 106
ASN A 322
 None
 1.21A 5hgcA-2f6aA:
undetectable		 5hgcA-2f6aA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 12 PRO A  93
ALA A 104
THR A  55
ILE A 106
PHE A 131
 None
 1.34A 5hgcA-2f6aA:
undetectable		 5hgcA-2f6aA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 2f6a COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 12 SER A 274
GLN A 267
SER A 231
GLY A 228
THR A 229
 None
 1.44A 5oj0A-2f6aA:
undetectable		 5oj0A-2f6aA:
18.92