SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		5 / 11 ALA A 192
ASN A  45
GLY A 185
ALA A  80
VAL A  98
 None
 1.18A 3rukD-2f6bA:
undetectable		 3rukD-2f6bA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		3 / 3 ARG A  49
TYR A 177
GLU A 178
 None
 0.71A 4zzbE-2f6bA:
undetectable		 4zzbE-2f6bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		4 / 7 ALA A  72
ARG A  49
GLY A  51
GLU A 178
 None
 1.02A 5btdA-2f6bA:
undetectable
5btdB-2f6bA:
undetectable
5btdC-2f6bA:
undetectable		 5btdA-2f6bA:
15.56
5btdB-2f6bA:
19.01
5btdC-2f6bA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		4 / 7 ALA A  72
ARG A  49
GLY A  51
GLU A 178
 None
 1.02A 5btdA-2f6bA:
undetectable
5btdC-2f6bA:
1.2
5btdD-2f6bA:
undetectable		 5btdA-2f6bA:
15.56
5btdC-2f6bA:
15.56
5btdD-2f6bA:
19.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		5 / 8 TYR A 125
THR A 127
ARG A 129
GLN A 143
TRP A 145
 None
 0.59A 5tzoA-2f6bA:
25.1		 5tzoA-2f6bA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		4 / 8 TRP A 104
THR A 127
ARG A 129
GLN A 143
 None
 1.06A 5tzoB-2f6bA:
25.2		 5tzoB-2f6bA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		5 / 8 TYR A 125
THR A 127
ARG A 129
GLN A 143
TRP A 145
 None
 0.42A 5tzoB-2f6bA:
25.2		 5tzoB-2f6bA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		5 / 8 TYR A 125
THR A 127
ARG A 129
GLN A 143
TRP A 145
 None
 0.51A 5tzoC-2f6bA:
25.0		 5tzoC-2f6bA:
47.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2f6b FAMILY 11 XYLANASE
(Bacillus) 		3 / 3 LEU A 199
ILE A  68
TYR A  95
 None
 0.62A 5uunB-2f6bA:
undetectable		 5uunB-2f6bA:
20.06