SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.37A 2f78A-2f6gA:
34.4		 2f78A-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		7 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.63A 2f78A-2f6gA:
34.4		 2f78A-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.36A 2f78B-2f6gA:
33.5		 2f78B-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		7 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
THR A 267
 None
 0.55A 2f78B-2f6gA:
33.5		 2f78B-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.18A 2f7aA-2f6gA:
33.6		 2f7aA-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_B_ACTB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 4 HIS A 116
PRO A 117
ASN A 118
TYR A 281
 None
 0.77A 2f7aB-2f6gA:
32.1		 2f7aB-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		9 / 9 LEU A 100
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.57A 2f7aB-2f6gA:
32.1		 2f7aB-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		6 / 6 VAL A  97
SER A  99
ARG A 146
LEU A 147
PHE A 203
HIS A 206
 None
 0.68A 2f8dA-2f6gA:
33.3		 2f8dA-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		10 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.39A 2f8dA-2f6gA:
33.3		 2f8dA-2f6gA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		10 / 10 LEU A 100
GLY A 103
LEU A 104
LEU A 105
ILE A 108
PHE A 144
LEU A 159
ARG A 160
ILE A 269
TYR A 293
 None
 0.41A 2f8dB-2f6gA:
33.4		 2f8dB-2f6gA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		6 / 11 GLY A 143
ALA A 142
ASP A 141
ILE A  92
ILE A 108
ILE A 282
 None
 1.37A 2r5qB-2f6gA:
undetectable		 2r5qB-2f6gA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		6 / 10 GLY A 143
ALA A 142
ASP A 141
ILE A  92
ILE A 108
ILE A 282
 None
 1.37A 2r5qD-2f6gA:
undetectable		 2r5qD-2f6gA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 8 ILE A 221
PHE A 211
VAL A 166
LEU A 242
 None
 0.87A 2w98B-2f6gA:
undetectable		 2w98B-2f6gA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 6 ASN A 175
SER A 171
ALA A 170
HIS A 169
 None
 1.26A 3aruA-2f6gA:
undetectable		 3aruA-2f6gA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 8 GLY A 232
LEU A 231
LEU A 252
ILE A 250
 None
 0.87A 3nbqC-2f6gA:
undetectable		 3nbqC-2f6gA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 7 ALA A 170
SER A 256
VAL A 258
VAL A 168
 None
 0.88A 3o14A-2f6gA:
undetectable		 3o14A-2f6gA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 6 LEU A 184
PRO A 218
LEU A 187
LEU A 194
 None
 0.62A 3q1eA-2f6gA:
0.0
3q1eC-2f6gA:
0.0		 3q1eA-2f6gA:
19.27
3q1eC-2f6gA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 6 LEU A 194
LEU A 184
PRO A 218
LEU A 187
 None
 0.73A 3q1eA-2f6gA:
0.0
3q1eC-2f6gA:
0.0		 3q1eA-2f6gA:
19.27
3q1eC-2f6gA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		5 / 12 LEU A 147
GLY A 145
GLN A 131
LEU A 100
THR A 267
 None
 1.27A 4olmA-2f6gA:
undetectable		 4olmA-2f6gA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2f6g HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM
(Acinetobacter
baylyi) 		4 / 7 ALA A 245
PHE A 211
ILE A 210
ILE A 240
 None
 0.88A 6b5vB-2f6gA:
undetectable
6b5vD-2f6gA:
undetectable		 6b5vB-2f6gA:
20.25
6b5vD-2f6gA:
20.25