SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 LEU A 188
MET A 233
TYR A 230
LEU A 210
 None
 0.99A 1kt3A-2f6kA:
undetectable		 1kt3A-2f6kA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.94A 1rxcB-2f6kA:
undetectable		 1rxcB-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 1.05A 1rxcC-2f6kA:
undetectable		 1rxcC-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 1.02A 1rxcD-2f6kA:
undetectable		 1rxcD-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.97A 1rxcE-2f6kA:
undetectable		 1rxcE-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.94A 1rxcF-2f6kA:
undetectable		 1rxcF-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.94A 1rxcK-2f6kA:
undetectable		 1rxcK-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.95A 1rxcL-2f6kA:
undetectable		 1rxcL-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 1v54A-2f6kA:
undetectable		 1v54A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 1v54N-2f6kA:
undetectable		 1v54N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 1v55A-2f6kA:
undetectable		 1v55A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 1v55N-2f6kA:
undetectable		 1v55N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 LEU A  54
LEU A  83
ALA A  84
LEU A  41
MET A  44
 None
 1.37A 2aa6A-2f6kA:
undetectable		 2aa6A-2f6kA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 2dyrA-2f6kA:
undetectable		 2dyrA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 2dyrN-2f6kA:
undetectable		 2dyrN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 2dysA-2f6kA:
undetectable		 2dysA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 2dysN-2f6kA:
undetectable		 2dysN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.71A 2eijA-2f6kA:
undetectable		 2eijA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 2eijN-2f6kA:
undetectable		 2eijN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.70A 2eikA-2f6kA:
undetectable		 2eikA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 2eikN-2f6kA:
1.6		 2eikN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.72A 2eilA-2f6kA:
1.7		 2eilA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 2eilN-2f6kA:
undetectable		 2eilN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 2eimA-2f6kA:
undetectable		 2eimA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.71A 2eimN-2f6kA:
undetectable		 2eimN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.71A 2einA-2f6kA:
undetectable		 2einA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 ASP A  79
LEU A  54
THR A   8
HIS A   9
HIS A 154
 None
None
None
MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
 1.37A 2jihA-2f6kA:
undetectable		 2jihA-2f6kA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A   7
HIS A   9
HIS A 154
 MN  A 402 (-3.3A)
MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
 0.46A 2ozrF-2f6kA:
undetectable		 2ozrF-2f6kA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 ASP A  46
ASN A  47
THR A   8
 None
 0.61A 2pymB-2f6kA:
undetectable		 2pymB-2f6kA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 ASP A  46
ASN A  47
THR A   8
 None
 0.58A 2q63B-2f6kA:
undetectable		 2q63B-2f6kA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 LEU A 144
TYR A 141
GLN A 142
 None
 0.73A 2wekA-2f6kA:
undetectable		 2wekA-2f6kA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 11 SER A 265
THR A 270
SER A 275
GLY A 264
ALA A 241
 None
 1.48A 2xh9A-2f6kA:
undetectable		 2xh9A-2f6kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 SER A 265
THR A 270
SER A 275
GLY A 264
ALA A 241
 None
 1.46A 2xh9B-2f6kA:
undetectable		 2xh9B-2f6kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 2y69A-2f6kA:
undetectable		 2y69A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.77A 2zxwA-2f6kA:
undetectable		 2zxwA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 2zxwN-2f6kA:
1.8		 2zxwN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.78A 3ablN-2f6kA:
undetectable		 3ablN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 3abmA-2f6kA:
undetectable		 3abmA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 3abmN-2f6kA:
undetectable		 3abmN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 3ag1A-2f6kA:
undetectable		 3ag1A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 3dtuA-2f6kA:
undetectable		 3dtuA-2f6kA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 8 GLY A 120
ALA A 118
ASP A 116
GLY A  80
LEU A  54
 None
 1.33A 3em6A-2f6kA:
undetectable		 3em6A-2f6kA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 ASP A  79
LEU A  54
THR A   8
HIS A   9
HIS A 154
 None
None
None
MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
 1.29A 3hy7A-2f6kA:
undetectable		 3hy7A-2f6kA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 ASP A  79
LEU A  54
THR A   8
HIS A   9
HIS A 154
 None
None
None
MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
 1.31A 3hy7B-2f6kA:
undetectable		 3hy7B-2f6kA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 ASN A 156
ASP A 266
HIS A   7
HIS A 205
 None
MN  A 402 (-2.7A)
MN  A 402 (-3.3A)
None
 1.03A 3t01A-2f6kA:
undetectable		 3t01A-2f6kA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 VAL A 236
ILE A 185
LEU A 188
PHE A 192
VAL A 232
 None
 1.05A 3w68B-2f6kA:
undetectable		 3w68B-2f6kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 VAL A 236
ILE A 185
LEU A 188
PHE A 192
VAL A 232
 None
 1.13A 3w68C-2f6kA:
2.1		 3w68C-2f6kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.74A 3wg7A-2f6kA:
undetectable		 3wg7A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 3wg7N-2f6kA:
undetectable		 3wg7N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.40A 3zncA-2f6kA:
undetectable		 3zncA-2f6kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 ASP A 266
ALA A 241
GLY A 264
HIS A 154
HIS A 205
 MN  A 402 (-2.7A)
None
None
MN  A 402 (-3.3A)
None
 1.10A 4c5nB-2f6kA:
undetectable		 4c5nB-2f6kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.43A 4coqB-2f6kA:
undetectable		 4coqB-2f6kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.93A 4e1vA-2f6kA:
undetectable		 4e1vA-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.94A 4e1vB-2f6kA:
undetectable		 4e1vB-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.94A 4e1vC-2f6kA:
undetectable		 4e1vC-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.95A 4e1vD-2f6kA:
undetectable		 4e1vD-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.96A 4e1vE-2f6kA:
undetectable		 4e1vE-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.97A 4e1vG-2f6kA:
undetectable		 4e1vG-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLN A 111
ILE A  70
VAL A  73
PRO A  98
 None
 0.95A 4e1vH-2f6kA:
undetectable		 4e1vH-2f6kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 5 TYR A 269
THR A 108
LEU A  97
THR A 125
 None
 1.34A 4mbsB-2f6kA:
undetectable		 4mbsB-2f6kA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 ASP A   5
ARG A 276
THR A   8
 None
 0.90A 4p3rA-2f6kA:
undetectable		 4p3rA-2f6kA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 VAL A 140
LEU A 144
VAL A 109
 None
 0.50A 4wq4A-2f6kA:
undetectable		 4wq4A-2f6kA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 6 ILE A 203
PRO A 204
HIS A   9
ILE A  53
 None
None
MN  A 402 (-3.5A)
None
 0.96A 4zj8A-2f6kA:
undetectable		 4zj8A-2f6kA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.77A 5b1aN-2f6kA:
undetectable		 5b1aN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 5 TRP A  30
LEU A  11
PRO A  33
LEU A  54
 None
 1.29A 5eshA-2f6kA:
undetectable		 5eshA-2f6kA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.49A 5jn8C-2f6kA:
undetectable		 5jn8C-2f6kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.46A 5jn8D-2f6kA:
undetectable		 5jn8D-2f6kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.47A 5jncD-2f6kA:
undetectable		 5jncD-2f6kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.49A 5ku6B-2f6kA:
undetectable		 5ku6B-2f6kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 HIS A   9
HIS A 154
HIS A   7
LEU A  94
THR A 122
 MN  A 402 (-3.5A)
MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
None
 1.49A 5ku6D-2f6kA:
undetectable		 5ku6D-2f6kA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 205
ASP A 239
HIS A   7
 None
None
MN  A 402 (-3.3A)
 0.92A 5n1tW-2f6kA:
undetectable		 5n1tW-2f6kA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.72A 5x1bA-2f6kA:
undetectable		 5x1bA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 5x1fA-2f6kA:
undetectable		 5x1fA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 ASP A 214
GLY A 211
PHE A 209
TYR A 230
ALA A 218
 None
 1.45A 5x66D-2f6kA:
undetectable		 5x66D-2f6kA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 5z84A-2f6kA:
undetectable		 5z84A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 5z84N-2f6kA:
undetectable		 5z84N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.78A 5z85A-2f6kA:
1.8		 5z85A-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.75A 5z85N-2f6kA:
undetectable		 5z85N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.78A 5z86N-2f6kA:
undetectable		 5z86N-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.77A 5zcoA-2f6kA:
undetectable		 5zcoA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.73A 5zcoN-2f6kA:
undetectable		 5zcoN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.75A 5zcpA-2f6kA:
undetectable		 5zcpA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.78A 5zcpN-2f6kA:
undetectable		 5zcpN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.75A 5zcqA-2f6kA:
undetectable		 5zcqA-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 5zcqN-2f6kA:
undetectable		 5zcqN-2f6kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 VAL A  61
TYR A  15
HIS A 154
TYR A  10
 None
None
MN  A 402 (-3.3A)
None
 0.90A 6gneB-2f6kA:
undetectable		 6gneB-2f6kA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2f6k METAL-DEPENDENT
HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 HIS A 154
HIS A   7
HIS A 205
 MN  A 402 (-3.3A)
MN  A 402 (-3.3A)
None
 0.76A 6nknA-2f6kA:
undetectable		 6nknA-2f6kA:
22.12