SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 2f6n BROMODOMAIN PHD
FINGER TRANSCRIPTION
FACTOR
(Homo
sapiens) 		3 / 3 ASP A 136
VAL A 122
LEU A  81
 None
 0.60A 5e5jB-2f6nA:
undetectable		 5e5jB-2f6nA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 2f6n BROMODOMAIN PHD
FINGER TRANSCRIPTION
FACTOR
(Homo
sapiens) 		4 / 6 PRO A  92
VAL A  97
TYR A 105
ASN A 148
 None
 0.49A 5pbeA-2f6nA:
17.9		 5pbeA-2f6nA:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2f6n BROMODOMAIN PHD
FINGER TRANSCRIPTION
FACTOR
(Homo
sapiens) 		4 / 8 VAL A  97
CYH A 144
TYR A 147
ASN A 148
 None
 0.50A 5y1yA-2f6nA:
16.3		 5y1yA-2f6nA:
26.70