SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		6 / 12 LEU A  38
GLY A 103
GLY A 101
ILE A 168
SER A   7
LEU A   8
 None
PO4  A5001 (-3.6A)
PO4  A5001 (-3.7A)
None
None
None
 1.46A 1v2xA-2f6sA:
undetectable		 1v2xA-2f6sA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		5 / 7 GLU A  75
GLY A  30
GLN A  32
PHE A  98
ILE A  49
 None
 1.18A 2qmzA-2f6sA:
undetectable
2qmzB-2f6sA:
undetectable		 2qmzA-2f6sA:
19.18
2qmzB-2f6sA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		3 / 3 GLY A  47
PRO A  97
LEU A  31
 None
 0.60A 3hcpB-2f6sA:
undetectable		 3hcpB-2f6sA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		5 / 12 TYR A  89
LEU A 149
LEU A 150
ALA A 131
TYR A 132
 None
 0.78A 3vw7A-2f6sA:
undetectable		 3vw7A-2f6sA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		4 / 8 PHE A  98
HIS A  35
GLU A  33
ILE A  28
 None
 1.35A 4cx7A-2f6sA:
undetectable
4cx7B-2f6sA:
undetectable		 4cx7A-2f6sA:
19.25
4cx7B-2f6sA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		5 / 10 ILE A 165
ALA A  11
ILE A 108
ILE A  20
ILE A 121
 None
 0.96A 5mvmD-2f6sA:
undetectable
5mvmE-2f6sA:
undetectable		 5mvmD-2f6sA:
13.99
5mvmE-2f6sA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2f6s CELL FILAMENTATION
PROTEIN, PUTATIVE
(Helicobacter
pylori) 		5 / 12 SER A   7
ILE A  15
HIS A  35
LEU A  42
TYR A  43
 None
 1.49A 5ycpA-2f6sA:
undetectable		 5ycpA-2f6sA:
18.91