SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		6 / 12 ASN A  61
PHE A  63
THR A  73
VAL A  83
LEU A  91
THR A 102
 None
 0.75A 3elzA-2f73A:
17.2		 3elzA-2f73A:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		5 / 12 ASN A  61
THR A  73
VAL A  83
LEU A  91
THR A 102
 None
 0.77A 3elzC-2f73A:
14.8		 3elzC-2f73A:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		5 / 12 ASN A  61
THR A  73
VAL A  83
LEU A  91
THR A 102
 None
 0.77A 3em0B-2f73A:
17.7		 3em0B-2f73A:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		6 / 12 PHE A  18
ILE A  22
ASN A  61
VAL A  83
LEU A  91
THR A 102
 None
 0.43A 3em0B-2f73A:
17.7		 3em0B-2f73A:
36.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		4 / 5 PHE A  50
ILE A  41
PHE A  48
PHE A  63
 None
 1.06A 3owxB-2f73A:
undetectable		 3owxB-2f73A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 2f73 FATTY ACID-BINDING
PROTEIN, LIVER
(Homo
sapiens) 		4 / 5 SER A   0
GLN A  43
LEU A  91
PHE A   3
 None
 1.35A 5evyX-2f73A:
undetectable		 5evyX-2f73A:
17.49