SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2f7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 LEU A 419
SER A 287
ASN A 328
 None
 0.70A 1bx4A-2f7lA:
undetectable		 1bx4A-2f7lA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 TYR A 268
LEU A 348
LEU A 352
LEU A 322
TYR A 333
 None
 1.26A 1fmlA-2f7lA:
undetectable		 1fmlA-2f7lA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
 None
 1.06A 1hsgB-2f7lA:
undetectable		 1hsgB-2f7lA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 160
CYH A 197
HIS A 162
LEU A 348
HIS A 336
 None
 1.37A 1ie9A-2f7lA:
undetectable		 1ie9A-2f7lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 THR A 143
GLU A  58
ASP A  51
 None
 0.77A 1nt2A-2f7lA:
undetectable		 1nt2A-2f7lA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 ASP A  45
THR A  76
GLU A 115
 None
 0.71A 1pj7A-2f7lA:
undetectable		 1pj7A-2f7lA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 11 SER A  63
LEU A  61
ILE A  94
ILE A  56
VAL A  54
 None
 1.03A 1pkvA-2f7lA:
undetectable
1pkvB-2f7lA:
undetectable		 1pkvA-2f7lA:
12.69
1pkvB-2f7lA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A  56
VAL A  54
SER A  63
LEU A  61
ILE A  94
 None
 1.02A 1pkvA-2f7lA:
undetectable
1pkvB-2f7lA:
undetectable		 1pkvA-2f7lA:
12.69
1pkvB-2f7lA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A 356
TRP A 269
LYS A 414
 None
 1.39A 1qu2A-2f7lA:
undetectable		 1qu2A-2f7lA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 11 VAL A  57
GLY A  59
VAL A 145
ASP A  70
VAL A  68
 None
 1.27A 2a1nA-2f7lA:
undetectable		 2a1nA-2f7lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		6 / 12 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
VAL A 183
 None
 1.35A 2avsB-2f7lA:
undetectable		 2avsB-2f7lA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 7 MET A 344
TYR A 155
HIS A 162
HIS A 336
 None
 1.44A 2bytA-2f7lA:
undetectable		 2bytA-2f7lA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 7 MET A 344
TYR A 155
HIS A 162
HIS A 336
 None
 1.44A 2bytD-2f7lA:
undetectable		 2bytD-2f7lA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 10 VAL A  57
GLY A  59
VAL A 145
ASP A  70
VAL A  68
 None
 1.34A 2cp4A-2f7lA:
undetectable		 2cp4A-2f7lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A  40
VAL A  64
GLY A  65
GLY A  35
 None
 0.81A 2wd9A-2f7lA:
undetectable		 2wd9A-2f7lA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 5 GLN A  80
ASP A   8
ASP A 241
THR A  95
 None
 1.34A 3bwcB-2f7lA:
1.8		 3bwcB-2f7lA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 ASN A 205
ALA A 212
GLY A 184
VAL A 228
THR A 225
 None
 1.10A 3c6gB-2f7lA:
undetectable		 3c6gB-2f7lA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 ASN A 203
ASN A 181
ILE A 248
GLY A 329
THR A 218
 None
 1.12A 3eeyB-2f7lA:
undetectable		 3eeyB-2f7lA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 ASN A 203
ASN A 181
ILE A 248
GLY A 329
THR A 218
 None
 1.11A 3eeyI-2f7lA:
undetectable		 3eeyI-2f7lA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 8 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
 None
 1.11A 3ekpA-2f7lA:
undetectable		 3ekpA-2f7lA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A 234
ILE A 199
TYR A 200
ILE A 177
 None
 1.01A 3hgxA-2f7lA:
undetectable		 3hgxA-2f7lA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 423
GLY A 424
THR A 425
 SO4  A 460 (-3.5A)
SO4  A 460 (-3.8A)
SO4  A 460 (-4.1A)
 0.19A 3k9wA-2f7lA:
undetectable		 3k9wA-2f7lA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 ASP A 243
SER A  97
ARG A 246
 None
 0.97A 3loqA-2f7lA:
undetectable		 3loqA-2f7lA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 8 PHE A 133
VAL A  64
GLY A  60
GLY A  31
 None
 0.72A 3n9jB-2f7lA:
undetectable		 3n9jB-2f7lA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		6 / 12 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
VAL A 183
 None
 1.31A 3nu5A-2f7lA:
undetectable		 3nu5A-2f7lA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		6 / 12 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
VAL A 183
 None
 1.28A 3nu5B-2f7lA:
undetectable		 3nu5B-2f7lA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
 None
 1.08A 3nu6B-2f7lA:
undetectable		 3nu6B-2f7lA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLY A 105
ILE A  56
VAL A  57
 None
 0.50A 3nv6A-2f7lA:
undetectable		 3nv6A-2f7lA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		6 / 9 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
VAL A 183
 None
 1.30A 3oxvC-2f7lA:
undetectable		 3oxvC-2f7lA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		6 / 10 ASP A 341
GLY A 342
ALA A 343
VAL A 156
GLY A 184
VAL A 183
 None
 1.27A 3oxwA-2f7lA:
undetectable		 3oxwA-2f7lA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 4 SER A 182
GLY A 105
GLU A  17
 None
 0.64A 3raeA-2f7lA:
undetectable
3raeC-2f7lA:
undetectable		 3raeA-2f7lA:
22.70
3raeC-2f7lA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 6 ALA A 239
ASP A 178
LEU A 222
THR A 218
 None
 1.09A 3rozA-2f7lA:
3.8		 3rozA-2f7lA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A 105
THR A  95
ASN A  99
GLY A   6
PHE A   5
 None
 0.98A 3sglA-2f7lA:
2.5		 3sglA-2f7lA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 8 ILE A 106
ILE A 124
PHE A   5
LEU A  61
VAL A  42
 None
 1.45A 3ua5A-2f7lA:
undetectable		 3ua5A-2f7lA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 4 LEU A 352
ILE A 281
TYR A 333
TYR A 294
 None
 1.36A 3vt7A-2f7lA:
undetectable		 3vt7A-2f7lA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 4 SER A 182
GLY A 105
GLU A  17
 None
 0.58A 4juoA-2f7lA:
undetectable
4juoC-2f7lA:
undetectable		 4juoA-2f7lA:
22.70
4juoC-2f7lA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 5 ASN A 328
GLY A 329
ASP A 112
ASP A 245
 None
 1.08A 4n48B-2f7lA:
undetectable		 4n48B-2f7lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 4 ASN A 328
GLY A 329
ASP A 112
ASP A 245
 None
 1.06A 4n49A-2f7lA:
undetectable		 4n49A-2f7lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  79
GLY A  91
LEU A  61
ILE A 106
VAL A  23
 None
 1.04A 4ok1A-2f7lA:
undetectable		 4ok1A-2f7lA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 ARG A  11
GLU A 216
TYR A 103
 None
 0.98A 4r29D-2f7lA:
undetectable		 4r29D-2f7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 348
LYS A 273
ASN A 274
ALA A 323
ILE A 281
 None
 1.13A 4x1kD-2f7lA:
undetectable		 4x1kD-2f7lA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		5 / 11 LEU A 348
LYS A 273
ASN A 274
ALA A 323
ILE A 281
 None
 1.18A 4x20D-2f7lA:
undetectable		 4x20D-2f7lA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 6 ARG A  11
ASP A 243
GLY A 242
ASP A 245
 None
 1.13A 5hp1C-2f7lA:
3.9		 5hp1C-2f7lA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 8 GLY A 242
ALA A 185
ASP A 178
PHE A 210
 None
 0.98A 5mvsB-2f7lA:
undetectable		 5mvsB-2f7lA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 161
HIS A 336
TYR A  81
 None
 1.00A 5y2tA-2f7lA:
undetectable		 5y2tA-2f7lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A  93
VAL A 109
LYS A 107
ASP A 245
 None
 0.81A 5yf9B-2f7lA:
undetectable		 5yf9B-2f7lA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE
(Sulfurisphaera
tokodaii) 		4 / 8 GLY A 196
LEU A 195
VAL A 156
LEU A 160
 None
 0.85A 6czmD-2f7lA:
undetectable
6czmF-2f7lA:
undetectable		 6czmD-2f7lA:
24.03
6czmF-2f7lA:
24.03